Long-term Follow-up of Gastric Adenocarcinoma with Chief Cell Differentiation Using Upper Gastrointestinal Tract Endoscopy
Long-term Follow-up of Gastric Adenocarcinoma with Chief Cell Differentiation Using Upper Gastrointestinal Tract Endoscopy
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DOI：
10.2169/internalmedicine.52.0361
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发表时间：
2013-01-01
影响因子：
1.2
通讯作者：
Yao, Takashi
中科院分区：
文献类型：
--
作者：
Abe, Takashi;Nagai, Takayuki;Yao, Takashi
在上消化道内镜筛查期间，发现一名71岁无症状女性在胃的上三分之一处有一个小的、黄色的、浅表的隆起病变，没有任何萎缩粘膜的迹象。该患者每年接受一次内窥镜随访，持续约5年;然而，几乎检测不到肿瘤的变化。进行内视镜黏膜切除术，组织学检查证实诊断为胃腺癌与主细胞分化（GA-CCD）。GA-CCD是罕见的，因此，其临床病理特征仍然未知。该病例表明，在长期随访期间，GA-CCD仅可观察到勉强可检测到的内镜变化。
During upper endoscopic screening, a 71-year-old asymptomatic woman was found to have a small, yellowish, superficial elevated lesion in the upper third of her stomach, without any signs of atrophic mucosa. The patient underwent endoscopic follow-up once a year for approximately five years; however, changes in the tumor were barely detectable. Endoscopic mucosal resection was performed, and a histological examination confirmed the diagnosis of gastric adenocarcinoma with chief cell differentiation (GA-CCD). GA-CCD is rare; therefore, its clinicopathological features remain unknown. This case suggests that only barely detectable endoscopic changes may be observed in GA-CCD during long-term follow-up.