Seasonal Redistribution of Immune Function in a Migrant Shorebird: Annual-Cycle Effects Override Adjustments to Thermal Regime
Seasonal Redistribution of Immune Function in a Migrant Shorebird: Annual-Cycle Effects Override Adjustments to Thermal Regime
复制标题
DOI：
10.1086/592865
复制
发表时间：
2008-12-01
影响因子：
2.9
通讯作者：
Tieleman, B. Irene
中科院分区：
文献类型：
--
作者：
Buehler, Deborah M.;Piersma, Theunis;Tieleman, B. Irene
在整个年度周期中，对竞争生理系统的需求会发生变化，动物必须分配资源以最大限度地提高适应性。免疫功能就是这样一个系统，对生存很重要。然而，大多数野生动物缺乏在整个年度周期内跟踪免疫功能的详细经验数据。我们每月一次，一年的组成性免疫指标对圈养红结（Calidris canutus）。我们还研究了温度作为免疫变异的环境因素，通过操纵环境温度来改变能量消耗。为了确定免疫指标之间的关系，我们进行了主成分分析。我们发现免疫指数在年周期中具有显着的重复性，并且个体内和个体之间的免疫指数存在协变。这种协变表明免疫策略作为个体之间的个体特征，并在个体内不同的年度周期阶段使用不同的免疫策略。在一年的周期，高成本的吞噬细胞为基础的免疫和低成本的淋巴细胞为基础的免疫是高质量的变化，但有一个明显的转变，以低成本的淋巴细胞为基础的免疫高峰期蜕皮。温度的实验操作对免疫功能的年度变化几乎没有影响。这表明，今后还应审查其他环境因素，如粮食供应和疾病。
Throughout the annual cycle, demands on competing physiological systems change, and animals must allocate resources to maximize fitness. Immune function is one such system and is important for survival. Yet detailed empirical data tracking immune function over the entire annual cycle are lacking for most wild animals. We measured constitutive immune indices once a month for a year on captive red knots (Calidris canutus). We also examined temperature as an environmental contributor to immune variation by manipulating ambient temperature to vary energy expenditure. To identify relationships among immune indices, we performed principal-component analysis. We found significant repeatability in immune indices over the annual cycle and covariation of immune indices within and among individuals. This covariation suggests immune strategies as individual traits among individuals and the use of different immune strategies during different annual-cycle stages within individuals. Over the annual cycle, both higher-cost phagocyte-based immunity and lower-cost lymphocyte-based immunity were high during mass change, but there was a clear shift toward lower-cost lymphocyte-based immunity during peak molt. Experimental manipulation of temperature had little effect on annual variation in immune function. This suggests that other environmental factors, such as food availability and disease, should also be examined in the future.