The effect of muscle atrophy in people with unilateral transtibial amputation for three activities: Gait alone does not tell the whole story
The effect of muscle atrophy in people with unilateral transtibial amputation for three activities: Gait alone does not tell the whole story
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DOI：
10.1016/j.jbiomech.2023.111484
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发表时间：
2023-02-13
影响因子：
2.4
通讯作者：
Bull, Anthony M. J.
中科院分区：
文献类型：
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作者：
Ding, Ziyun;Henson, David P.;Bull, Anthony M. J.
截肢给全世界数以百万计的肢体丧失者带来了巨大的运动挑战。残肢使用的减少导致肌肉萎缩，影响日常活动中的肌肉骨骼动力学。本研究的目的是量化基于磁共振（MR）成像的下肢肌肉体积差异，并将其与运动分析和肌肉骨骼模型相结合，以量化日常生活中关键活动的动态影响。8名创伤性单侧经胫骨截肢的男性参与者在接受最终义肢至少6个月后被招募。肌肉体积差异在膝关节伸肌处最大（35%,p = 0.008），其次是髋关节外展肌（17%,p = 0.008）。在运动分析实验室测量日常活动（水平行走，从椅子上站起来和上升一步），并使用详细的肌肉骨骼模型对单侧经胫截肢患者的肌肉和关节力进行量化，该模型根据截肢后受试者特定水平的肌肉体积差异进行校准。在所有活动中，残肢的膝关节伸肌力均低于完整肢(p
Amputation imposes significant challenges in locomotion to millions of people with limb loss worldwide. The decline in the use of the residual limb results in muscle atrophy that affects musculoskeletal dynamics in daily activities. The aim of this study was to quantify the lower limb muscle volume discrepancy based on magnetic resonance (MR) imaging and to combine this with motion analysis and musculoskeletal modelling to quantify the effects in the dynamics of key activities of daily living. Eight male participants with traumatic unilateral transtibial amputation were recruited who were at least six months after receiving their definitive prostheses. The muscle volume discrepancies were found to be largest at the knee extensors (35 %, p = 0.008), followed by the hip abductors (17 %, p = 0.008). Daily activities (level walking, standing up from a chair and ascending one step) were measured in a motion analysis laboratory and muscle and joint forces quantified using a detailed musculoskeletal model for people with unilateral transtibial amputation which was calibrated in terms of the muscle volume discrepancies post-amputation at a subject-specific level. Knee extensor muscle forces were lower at the residual limb than the intact limb for all activities (p