Metabolomics Fingerprinting of the Human Seminal Plasma of Asthenozoospermic Patients
Metabolomics Fingerprinting of the Human Seminal Plasma of Asthenozoospermic Patients
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DOI：
10.1002/mrd.22284
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发表时间：
2014-01-01
影响因子：
2.5
通讯作者：
Savadi-Shiraz, Elham
中科院分区：
文献类型：
--
作者：
Gilany, Kambiz;Moazeni-Pourasil, Roudabeh Sadat;Savadi-Shiraz, Elham
据估计，20%的夫妇不育，其中一半的不育病例与男性有关。其中一个条件，可以影响男性生育能力是弱精子症。我们将拉曼光谱应用于人精浆代谢物组的分析，并将化学计量学用于所获得的拉曼光谱的图案。弱精子症患者精浆代谢物组发生显著变化。摩尔Reprod. Dev. 81：84-86，2014. (c)2013 Wiley Periodicals，Inc.
It is estimated that 20% of couples are infertile, and half of these infertility cases are linked to men. One of conditions that can affect male fertility is asthenozoospermia. We applied Raman spectroscopy to the analysis of the metabolome of the human seminal plasma, and used chemometrics on the patterns of Raman spectra obtained. Significant changes were observed in the metabolome of the human seminal plasma of asthenozoospermic patients. Mol. Reprod. Dev. 81: 84-86, 2014. (c) 2013 Wiley Periodicals, Inc.