It's complicated - Factors predicting decisional conflict in prenatal diagnostic testing
It's complicated - Factors predicting decisional conflict in prenatal diagnostic testing
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DOI：
10.1111/hex.12363
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发表时间：
2016-04-01
影响因子：
3.2
通讯作者：
Cameron, Linda D.
中科院分区：
文献类型：
--
作者：
Muller, Cecile;Cameron, Linda D.
背景目前可用于检测胎儿遗传异常的存在的技术是复杂的，并且进行产前诊断测试可以具有广泛的影响。在个人能够确定是否参加这些测试之前，他们首先需要掌握产前基因检测的许多心理社会和临床方面。Objectives测试一个模型，该模型将关键的心理社会和临床因素整合为是否进行产前基因检测的决策冲突的预测因素。阅读四个假设场景之一，要求他们想象期待一个孩子，并考虑能够检测遗传条件的产前检查的选择;条件发作的年龄（出生与成年）及其可治愈性（无法治愈与可治愈）被操纵。参与者完成了决策冲突的措施，从正常的结果，测试反应的有效性，条件的一致性，儿童相关的担心，与其他父母的偏好，动机，以遵守医生的感知偏好，和paradity.ResultsPrenatal测试决策冲突的感知正常的结果是有益的，怀疑测试的可靠性，缺乏对遗传条件的了解，担心胎儿的健康，感知来自伴侣/配偶的意见分歧，想要遵循医生的偏好，并且没有孩子。讨论这些结果，随着怀孕护理中新技术的日益普及，可以告知沟通策略，促进夫妇的decisionmaking.ConclusionThis study provides insights into factors that might complicate premature testing decisionmaking.
BackgroundThe technologies currently available to detect the presence of foetal genetic abnormalities are complex, and undergoing prenatal diagnostic testing can have wide-ranging repercussions. Before individuals can decide with certainty whether or not to take these tests, they first need to grasp the many psychosocial and clinical dimensions of prenatal genetic testing.ObjectiveTo test a model integrating key psychosocial and clinical factors as predictors of decisional conflict in decisions about whether or not to undergo prenatal genetic testing.MethodAdults (n=457) read one of four hypothetical scenarios asking them to imagine expecting a child and considering the option of a prenatal test able to detect a genetic condition; age of condition onset (birth vs. adulthood) and its curability (no cure vs. curable) were manipulated. Participants completed measures of decisional conflict, perceived benefits from normal results, test response efficacy, condition coherence, child-related worry, perceived disagreement with the other parent's preference, motivation to comply with doctors' perceived preferences, and parity.ResultsPrenatal testing decisional conflict was positively predicted by perceiving normal results as beneficial, doubting the test's reliability, lacking understanding of the genetic condition, worrying about the health of the foetus, perceiving differences of opinion from partner/spouse, wanting to follow doctors' preferences, and being childless.DiscussionThese results, of growing relevance given the increasing availability of new technologies in pregnancy care, can inform communication strategies that facilitate coupless' decision making.ConclusionThis study provides insights into factors that might complicate prenatal testing decision making.