Impact of an exercise intervention on methamphetamine use outcomes post-residential treatment care.

Impact of an exercise intervention on methamphetamine use outcomes post-residential treatment care.
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DOI:
10.1016/j.drugalcdep.2015.08.029
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发表时间:
2015-11-01
影响因子:
4.2
通讯作者:
Cooper CB
Cooper CB
中科院分区:
医学2区
文献类型:
--
作者:
Rawson RA;Chudzynski J;Mooney L;Gonzales R;Ang A;Dickerson D;Penate J;Salem BA;Dolezal B;Cooper CB

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我们检查了8周运动干预对MA依赖个体在住院治疗后使用甲基苯丙胺(MA)的效果。135名新参加治疗的人被随机分配到一个结构化的8周运动干预组或健康教育对照组。大约在干预完成后1周,参与者被释放到社区。在住院后1个月、3个月和6个月收集访谈数据和尿液样本。在样本中,54.8%被归类为重度重度使用者(入院前一个月使用MA超过18天),45.2%被归类为重度轻度使用者(入院前一个月使用MA不超过18天)。使用混合多变量模型检查3个时间点间MA使用结果的组间差异。虽然在出院后1个月、3个月和6个月,与接受教育的参与者相比,运动参与者返回使用MA的人数较少,但差异无统计学意义。根据病情和MA严重程度,自我报告的MA使用和MA尿药检结果之间存在显著的相互作用:在出院后的三个时间点上,运动组中重度较低的使用者报告使用MA的天数明显少于教育组中重度较低的使用者。在三个时间点上,运动组中较低程度的使用者尿液阳性结果的百分比也低于教育组中较低程度使用者。这些关系在较严重的条件下的比较中不存在。结果支持运动作为治疗成分对于使用MA 18天或更少/月的个体的价值。
We examined the efficacy of an 8-week exercise intervention on posttreatment methamphetamine (MA) use among MA-dependent individuals following residential treatment. 135 individuals newly enrolled in treatment were randomly assigned to a structured 8-week exercise intervention or health education control group. Approximately 1 week after completion of the intervention, participants were discharged to the community. Interview data and urine samples were collected at 1-, 3-, and 6-months post-residential care. Of the sample, 54.8% were classified as higher severity users (using MA more than 18 days in the month before admission) and 45.2% as lower severity users (using MA for up to 18 days in the month before admission). Group differences in MA use outcomes were examined over the 3 timepoints using mixed-multivariate modeling. While fewer exercise participants returned to MA use compared to education participants at 1-, 3- and 6-months post-discharge, differences were not statistically significant. A significant interaction for self-reported MA use and MA urine drug test results by condition and MA severity was found: lower severity users in the exercise group reported using MA significantly fewer days at the three post-discharge timepoints than lower severity users in the education group. Lower severity users in the exercise group also had a lower percentage of positive urine results at the three timepoints than lower severity users in the education group. These relationships were not present in the comparison of the higher severity conditions. Results support the value of exercise as a treatment component for individuals using MA 18 or fewer days/month.