Arenavirus antibody in rodents indigenous to coastal southern California

Arenavirus antibody in rodents indigenous to coastal southern California
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DOI:
10.4269/ajtmh.2000.62.626
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发表时间:
2000-05-01
影响因子:
3.3
通讯作者:
Fulhorst, CF
Fulhorst, CF
中科院分区:
医学4区
文献类型:
--
作者:
Bennett, SG;Milazzo, ML;Fulhorst, CF

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本研究的目的是扩展我们对加州新世界沙粒病毒的地理和自然啮齿动物宿主范围的了解。对1,094只sigmodontine和112只鼠类啮齿动物的血清进行了白水阿罗约病毒和Amapari病毒抗体检测。在1,206只啮齿动物中有55只(4.6%)发现抗体:4只来自圣地亚哥县西北部,3只来自洛杉矶县,48只来自橙子县。抗体阳性鼠8只(7.8%)的103只褐翅瘤蛛中,1只在180只鳞翅目昆虫中,在32只鲍氏鼠中,8只其中,加州鹿鼠73只,占11.0%;艾氏鹿鼠85只,占1.2%;这项研究提供了新世界沙粒病毒发生在洛杉矶和橙子县和圣地亚哥县西北部的第一个证据,以及第一个证据表明Peromyscus和Reithrodontomys物种自然感染新世界沙粒病毒。
The purpose of this study was to extend our knowledge on the geographic and natural rodent host ranges of New World arenaviruses in California. Sera from 1,094 sigmodontine and 112 murine rodents were tested for antibody against Whitewater Arroyo and Amapari viruses. Antibody was found in 55 (4.6%) of the 1,206 rodents: 4 from northwestern San Diego County, 3 from Los Angeles County, and 48 from Orange County. The antibody positive rodents included 8 (7.8%) of 103 Neotoma fuscipes, 1 (0.6%) of 180 Neotoma lepida, 1 (3.1%) of 32 Peromyscus boylii, 8 (11.0%) of 73 Peromyscus californicus, 1 (1.2%) of 85 Peromyscus eremicus, 30 (8.5%) of 353 Peromyscus maniculatus, and 6 (2.2%) of 268 Reithrodontomys megalotis. This study provides the first evidence that New World arenaviruses occur in Los Angeles and Orange counties and northwestern San Diego County, and the first evidence that Peromyscus and Reithrodontomys species are naturally infected with New World arenaviruses.