Caries lesions after orthodontic treatment followed by quantitative light-induced fluorescence: a 2-year follow-up
Caries lesions after orthodontic treatment followed by quantitative light-induced fluorescence: a 2-year follow-up
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DOI：
10.1093/ejo/cjm008
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发表时间：
2007-06-01
影响因子：
2.6
通讯作者：
Zentner, A.
中科院分区：
文献类型：
--
作者：
Mattousch, T. J. H.;van der Veen, M. H.;Zentner, A.
本研究的目的是通过定量光诱导荧光(QLF)的方法，监测在正畸治疗后即刻和治疗后2年发现的白斑病变的自然行为。对51名年龄为12岁的受试者，男24名，女27名，在拔牙后即刻(T0)、后6周(T1)、6个月(T2)、2年(T3)分别用QLF进行龋病检查。使用专用软件测定任何病变的荧光损失[Delta F(%)]和面积[A(mm(2))]。病变的发展和性别的影响由一般线性模型(Friedman重复测量分析和双向重复测量方差分析)确定。使用QLF，在T0记录370个龋面。在研究期间，QLF分析丢失了19个病损，其中两个受试者的16个病损(Delta F-0=7.6-39.2%)被修复，3个病损的牙齿被拔除或冠。这导致了本研究纳入的351个病变，T0处的Delta F中位数为8.5%(四分位数6.6%；11.9%)。病变从早期(Delta F<；10%，n=227)到晚期(Delta F>；25%，n=6)不等。总体而言，在T0和T2之间，皮损有改善(P<；0.01)，但在T3时没有进一步的显著改善。35个皮损在2年后明显恶化。大多数病损(n=171)被认为是稳定的，145个病损明显改善，其中只有10个病损改善到消失的程度。在正畸治疗过程中形成的白斑病损在矫治器移除后改善的能力非常有限。有必要进行进一步的研究，以探讨预防措施的潜力，以促进病变的改善。
The aim of this study was to monitor, by means of quantitative light-induced fluorescence (QLF), the natural behaviour of white spot lesions detected immediately after orthodontic treatment and 2 years post-treatment. The buccal tooth surfaces of 51 subjects (>= 12 years), 24 males and 27 females, were examined with QLF for the presence of caries immediately after debonding (T0), and 6 weeks (T1), 6 months (T2), and 2 years (T3) thereafter. The fluorescence loss [Delta F(per cent)] and area [A (mm(2))] of any lesions were determined using dedicated software. The lesion development and influence of gender were determined by a general linear model (Friedman repeated-measures analysis and two-way repeated-measures analysis of variance).Using QLF, 370 carious surfaces were recorded at T0. During the study, 19 lesions were lost from QLF analysis of which 16 lesions (Delta F-0 = 7.6-39.2 per cent) in two subjects were restored and three teeth with lesions were extracted or crowned. This resulted in 351 lesions that were included in this study with a median Delta F at T0 of 8.5 per cent (quartiles 6.6 per cent; 11.9 per cent). The lesions varied from incipient (Delta F < 10 per cent, n = 227) to advanced (Delta F > 25 per cent, n = 6). Overall, the lesions showed improvement between T0 and T2 (P < 0.01) but no further significant improvement at T3. Thirty-five lesions became significantly worse after 2 years. The majority of lesions (n = 171) were considered to be stable, and 145 lesions improved significantly of which only 10 lesions improved to such an extent that they disappeared.White spot lesions developed during orthodontic treatment have very limited ability to improve after appliance removal. Further research to investigate the potential of preventive measures to enhance lesion improvement is necessary.