Evaluation of application possibility of water containing organic acids for chemical denture cleaning for older adults.
Evaluation of application possibility of water containing organic acids for chemical denture cleaning for older adults.
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含有机酸水用于老年人化学义齿清洁的应用可能性评价。
DOI：
10.1111/ggi.12467
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发表时间：
2015
期刊：
影响因子：
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通讯作者：
Sakurai K.
中科院分区：
文献类型：
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作者：
Izumi S;Ryu M;Ueda T;Ishihara K;Sakurai K.
目的通过微生物调查研究，评价几种有机酸作为食品添加剂制成的含有机酸水（WOA）在老年人义齿化学清洁中的应用可能性。方法采用抗菌菌膜法测定WOA对血链球菌、S。肺炎和白色念珠菌附着在热固化丙烯酸树脂上。将标本分为三组：对照组（TW）、商用义齿清洁剂组（DC）和WOA组（WOA）。样品分别处理5分钟、30分钟或8小时，通过计数菌落形成单位或三磷酸腺苷分析来确定附着微生物的数量。采用anin体内生物膜研究方法，对60例全口义齿的修复效果进行了研究。将义齿和盲牙随机分为上述三组，治疗10 min。通过计数菌落形成单位来确定治疗前后附着在义齿上的微生物数量。结果WOA与TW在菌膜研究中，除白色念珠菌外，WOA与DC之间无显著差异，WOA与TW在菌膜研究中有显著差异。WOA与DC的体内生物膜研究中，WOA与DC之间无显著性差异，WOA与DC之间有显著性差异。结论含有机酸水抗菌效果与市售义齿清洗剂相当，具有用于老年人义齿安全化学清洗的应用前景。Geriatr Gerontol Int 2015；16: 300 - 306。
AimThe purpose of the present study was to evaluate the application possibility of water containing organic acids (WOA), made by some organic acids used as food additives, for chemical denture cleaning for older adults by microbial investigation.MethodsUsing anin vitrobiofilm study, we determined the effects of WOA onStreptococcus sanguinis,S. pneumoniaeandCandida albicansattached to heat‐cured acrylic resins. Specimens were divided into three groups as follows: control group (TW), commercial denture cleaner group (DC) and WOA group (WOA). Specimens were treated with each for 5 min, 30 min or 8 h, and the numbers of attached microbes were determined by counting colony‐forming units or adenosine triphosphate analysis. Using anin vivobiofilm study, we studied the effects of these same solutions on 60 complete dentures. The dentures were divided randomly and blindness into three groups as described above, and treated for 10 min. The numbers of microbes attached to dentures before and after treatment were determined by counting colony‐forming units.ResultsFor thein vitrobiofilm study, there were significant differences in the numbers of microbes between WOA and TW, although there were no significant differences between WOA and DC except forC. albicans. For thein vivobiofilm study, there were significant differences between WOA, DC and TW, although there was no significant difference between WOA and DC.ConclusionWe conclude that water containing organic acids exerts antimicrobial effects as strong as commercial denture cleaner, and it has an application possibility of use for safe chemical denture cleaning for older adults.Geriatr Gerontol Int 2015; 16: 300–306.