Corneal higher-order aberrations of the anterior surface, posterior surface, and total cornea after small incision lenticule extraction (SMILE): high myopia versus mild to moderate myopia.
Corneal higher-order aberrations of the anterior surface, posterior surface, and total cornea after small incision lenticule extraction (SMILE): high myopia versus mild to moderate myopia.
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小切口微透镜摘除 (SMILE) 后前表面、后表面和全角膜的角膜高阶像差：高度近视与轻度至中度近视。
DOI：
10.1186/s12886-018-0965-1
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发表时间：
2018-11-12
影响因子：
2
通讯作者：
Yao K
中科院分区：
文献类型：
--
作者：
Jin HY;Wan T;Yu XN;Wu F;Yao K
目的探讨高度近视和轻、中度近视患者小切口晶状体摘除(SMILE)术后角膜前表面、后表面及全角膜的高阶像差。这项回顾性研究包括接受微笑手术的197只眼(101名患者)。根据术前等效球镜(SE)分为高度近视组(− 6.0D以上，H组)和轻中度近视组(− 6.0D以下，M组)。术前、术后3个月用Scheimpflg相机测量角膜前表面、后表面和全角膜的HOA。皮尔逊相关分析用于确定角膜像差与自发性角膜屈光度的关系。微笑手术前两组角膜前表面、后表面和全角膜的三至八级像差(RMSHOA)差异无统计学意义。然而，微笑后，两组的角膜前部和整体HOA，尤其是垂直昏迷和球差显著增加(P<； 0.0167)，而角膜后部HOA相对稳定(P& 0.0167)。H组术后HOA的诱发率明显高于M组(P<； 0.0167)。前表面和总角膜HOA的改变，特别是垂直眼球后差和球差的改变，与SE有关(p<； 0.05)。微笑后，两组患者的前部和全角膜HOA，特别是垂直昏迷和球差显著增加，而后部HOA保持稳定。异常改变与SE有关。追溯性注册。ChiCTR-ORC-17011040。已于2017年4月1日注册。注册名称：角膜屈光手术后临床效果观察。第一次参加试验的数据：2016年12月15日。
To investigate corneal higher-order aberrations (HOAs) of the anterior surface, posterior surface, and total cornea after small incision lenticule extraction (SMILE) in high myopic and mild to moderate myopic patients. This retrospective study included 197 eyes (101 patients) undergoing SMILE surgery. According to the preoperative spherical equivalent (SE), treated eyes were divided into two groups: a high myopic group (more than − 6.0 D, Group H) and a mild to moderate myopic group (less than − 6.0 D, Group M). Corneal HOAs of the anterior surface, posterior surface, and total cornea were measured using a Scheimpflug camera preoperatively and 3 months postoperatively. Pearson’s correlation analysis was conducted to determine relationships between corneal aberrations and the SE. There were no significant differences in third-order to eight-order aberrations (RMS HOAs) of the anterior surface, posterior surface, and total corneal between the two groups before SMILE surgery. However, after SMILE, anterior and total corneal HOAs, especially vertical coma and spherical aberrations, significantly increased in both groups (p < 0.0167), whereas posterior corneal HOAs remained relatively stable (p > 0.0167). The induction of HOAs was significantly greater in Group H than Group M postoperatively (p < 0.0167). Changes in anterior surface and total corneal HOAs, especially vertical coma and spherical aberrations, were related to the SE (p < 0.05). Anterior and total corneal HOAs, particularly vertical coma and spherical aberrations, significantly increased after SMILE in both groups, whereas posterior corneal HOAs remained stable. Aberration changes were related to SE. Retrospectively registered. ChiCTR-ORC-17011040. Registered 1 April 2017. Name of registry: The observation of clinical results after corneal refractive surgery. Data of enrolment of the first participant to the trial: 15 December 2016.
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