Iron-Catalyzed Intramolecular C(sp2)-H Amination
Iron-Catalyzed Intramolecular C(sp2)-H Amination
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DOI：
10.1002/anie.201510045
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发表时间：
2016-01-22
影响因子：
16.6
通讯作者：
Plietker, Bernd
中科院分区：
文献类型：
--
作者：
Alt, Isabel T.;Plietker, Bernd
亲核铁络合物Bu4N[Fe(CO)(3)-(NO)](TBA[Fe])催化α-叠氮二芳基和(叠氮芳基)烯在分子内直接C-H胺化生成相应的咔唑和吲哚，反应条件温和，催化剂用量低。这些特点和广泛的官能团耐受性使得这种方法成为一种特别有吸引力的方法，可以替代已有的基于贵金属的手术。
The nucleophilic iron complex Bu4N[Fe(CO)(3)-(NO)] (TBA[Fe]) catalyzes the direct intramolecular C-H amination of alpha-azidobiaryls and (azidoaryl) alkenes into the corresponding carbazoles and indoles, respectively, under mild conditions and with low catalyst loadings. These features and the broad functional-group tolerance render this method a particularly attractive alternative to established noblemetal-based procedures.