Open fetal surgery for life-threatening fetal anomalies

Open fetal surgery for life-threatening fetal anomalies
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DOI:
10.1016/j.siny.2009.05.003
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发表时间:
2010-02-01
影响因子:
3
通讯作者:
Adzick, N. Scott
Adzick, N. Scott
中科院分区:
医学3区
文献类型:
--
作者:
Adzick, N. Scott

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经过二十多年的实验和临床工作,胎儿手术是一种公认的治疗选择,高度选择胎儿有危及生命的异常。胎儿肺肿块伴积水通常是致命的。如果病变主要为实性或多囊性,则可在子宫内切除。胎儿骶尾翼畸胎瘤合并进行性高输出心力衰竭可能受益于子宫内肿瘤切除。重要的经验教训已经了解围手术期管理和产妇,胎儿和新生儿的结局后开放胎儿手术。2009爱思唯尔有限公司版权所有。
After more than two decades of experimental and clinical work, fetal surgery is an accepted treatment option for highly selected fetuses with life-threatening anomalies. Fetal lung masses associated with hydrops are usually fatal. These lesions can be resected in utero if they are predominantly solid or multicystic. Fetal sacrococcygeal teratoma complicated with progressive high output cardiac failure may benefit from in-Utero resection of the tumor. Important lessons have been learned about perioperative management and maternal, fetal, and neonatal outcomes after open fetal surgery. (C) 2009 Elsevier Ltd. All rights reserved.