Highly Stereoselective Synthesis of Tetrasubstituted Vinyl Selenides via Rhodium-Catalyzed [1,4]-Acyl Migration of Selenoesters and Diazo Compounds.
Highly Stereoselective Synthesis of Tetrasubstituted Vinyl Selenides via Rhodium-Catalyzed [1,4]-Acyl Migration of Selenoesters and Diazo Compounds.
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DOI：
10.1021/acs.orglett.2c00477
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发表时间：
2022-03
期刊：
影响因子：
5.2
通讯作者：
Xun Liu;Mingjia Li;Ke-Yan Dong;Shaoting Peng;Lu Liu
中科院分区：
文献类型：
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作者：
Xun Liu;Mingjia Li;Ke-Yan Dong;Shaoting Peng;Lu Liu
在这里，我们揭示了一种高立体选择性的Rh(II)催化的1，4-酰基重排硒的酯和α-重氮酮化合物，这提供了一个有效的方法来合成四取代乙烯基硒。此外，该反应还为中、大环化合物的合成提供了一种工具。
Herein, we disclose a highly stereoselective Rh(II)-catalyzed 1,4-acyl rearrangement of selenium esters and α-diazo carbonyl compounds, which provides an efficient method for synthesizing tetrasubstituted vinyl selenides. Furthermore, this reaction also offers a synthetic tool for medium and large ring compounds.