Cognitive stimulation for the treatment of Alzheimer's disease.
Cognitive stimulation for the treatment of Alzheimer's disease.
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DOI：
10.1586/14737175.8.5.751
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发表时间：
2008-05-01
影响因子：
4.3
通讯作者：
Orrell, Martin
中科院分区：
文献类型：
--
作者：
Spector, Aimee;Woods, Bob;Orrell, Martin
近年来，对痴呆症的社会心理干预措施的认识和使用有所增加。这与该领域高质量研究的增加以及英国对阿尔茨海默病药物治疗的限制相吻合。认知刺激疗法（cognitive stimulation therapy，CST）是一种针对轻度至中度痴呆症患者的简短团体治疗，基于现实取向和认知刺激的理论概念。它包括14个主题活动，通常每周两次，为期7周。一项多中心、随机对照试验显示，CST与不治疗相比，在认知和参与者评定的生活质量方面有显著益处。这些认知方面的益处与通过药物获得的益处相当，CST也被证明具有成本效益。受这项研究的影响，NICE发布的最新指南建议认知刺激仅作为治疗痴呆症认知症状的干预措施。这种观点描述了CST是如何开发和评估的，它在临床环境中的使用和未来调查的问题，如个性化CST。
In recent years, there has been an increase in the recognition and use of psychosocial interventions for dementia. This has coincided with an increase in high-quality research in the area, and restrictions in the use of drug therapies for Alzheimer's disease in the UK. Cognitive stimulation therapy (CST) is a brief group treatment for people with mild-to-moderate dementia, based on the theoretical concepts of reality orientation and cognitive stimulation. It involves 14 sessions of themed activities which typically run twice a week over a 7-week period. A multicenter, randomized controlled trial showed significant benefits in cognition and participant-rated quality of life when comparing CST versus no treatment. These benefits in cognition were comparable to those gained through medication, and CST also proved to be cost-effective. Influenced by this research, the latest guidelines released by NICE recommended cognitive stimulation only as an intervention for treating the cognitive symptoms of dementia. This perspective describes how CST was developed and evaluated, its use in clinical settings and issues for future investigation, such as individualized CST.