COVID-19 dynamics after a national immunization program in Israel
COVID-19 dynamics after a national immunization program in Israel
复制标题
DOI：
10.1038/s41591-021-01337-2
复制
发表时间：
2021-04-19
期刊：
影响因子：
82.9
通讯作者：
Segal, Eran
中科院分区：
文献类型：
--
作者：
Rossman, Hagai;Shilo, Smadar;Segal, Eran
对2020年8月28日至2021年2月24日期间收集的以色列卫生部数据进行的回顾性分析记录了国家疫苗接种运动对大流行动态的实际影响。迫切需要研究BNT162b2疫苗对2019冠状病毒病（COVID-19）的实际预防效果。在本研究中，我们对2020年8月28日至2021年2月24日期间收集的以色列卫生部数据进行了回顾性分析。我们研究了自2020年12月20日启动疫苗接种运动以来新发COVID-19病例数和住院人数的时间动态。为了将疫苗接种对病例和住院的可能影响与其他因素（包括2021年1月8日实施的第三次封锁）区分开来，我们进行了几项比较：(1)优先接种疫苗的60岁及以上人群与较年轻的年龄组；(2) 1月封锁与9月封锁；(3)早接种城市与晚接种城市的对比。根据疫苗接种优先顺序，60岁以上人群的COVID-19病例和住院人数下降幅度更大、更早，其次是更年轻的年龄组。在之前的封锁中没有观察到这种模式，在早期接种疫苗的城市中更为明显。我们的分析证明了国家疫苗接种运动对大流行动态的现实影响。
A retrospective analysis of data from the Israeli Ministry of Health collected between 28 August 2020 and 24 February 2021 documents the real-life effect of a national vaccination campaign on the pandemic dynamics.Studies on the real-life effect of the BNT162b2 vaccine for Coronavirus Disease 2019 (COVID-19) prevention are urgently needed. In this study, we conducted a retrospective analysis of data from the Israeli Ministry of Health collected between 28 August 2020 and 24 February 2021. We studied the temporal dynamics of the number of new COVID-19 cases and hospitalizations after the vaccination campaign, which was initiated on 20 December 2020. To distinguish the possible effects of the vaccination on cases and hospitalizations from other factors, including a third lockdown implemented on 8 January 2021, we performed several comparisons: (1) individuals aged 60 years and older prioritized to receive the vaccine first versus younger age groups; (2) the January lockdown versus the September lockdown; and (3) early-vaccinated versus late-vaccinated cities. A larger and earlier decrease in COVID-19 cases and hospitalization was observed in individuals older than 60 years, followed by younger age groups, by the order of vaccination prioritization. This pattern was not observed in the previous lockdown and was more pronounced in early-vaccinated cities. Our analysis demonstrates the real-life effect of a national vaccination campaign on the pandemic dynamics.