Behavior contingent processing of vestibular sensory signals in the vestibular nuclei.
Behavior contingent processing of vestibular sensory signals in the vestibular nuclei.
复制标题
前庭核中前庭感觉信号的行为偶然处理。
DOI：
10.1111/j.1749-6632.1996.tb15707.x
复制
发表时间：
1996
影响因子：
5.2
通讯作者：
Gdowski,GT
中科院分区：
文献类型：
--
作者：
McCrea,RA;Chen-Huang,C;Belton,T;Gdowski,GT
前庭感觉系统的表面目的是告知大脑头部的位置和运动。然而，这种感觉系统有点不寻常，因为感觉-运动整合发生在前庭信号中枢处理的第一阶段。许多从前庭神经接收直接输入的中枢次级前庭神经元也直接投射到运动神经元和/或在各种运动行为中发挥重要作用。例如，外侧前庭脊髓束神经元不仅携带与头部运动相关的信号，而且在运动过程中也受到相位调制。投射到眼外运动核的次级前庭神经元不仅携带与正在进行的头部运动有关的信号，而且还携带与眼睛位置或平滑追踪眼睛速度有关的信号，即使在没有头部运动的情况下。在许多情况下，同一个中枢神经元既是次级感觉神经元，又是重要的运动前通路的组成部分。因此，这也许并不奇怪，许多，如果不是大多数，在前庭核神经元表现出复杂的组合的感觉和运动signals 4在本文中，我们简要地描述了几种类型的实验中，单单位录音的结果，从松鼠猴中央二级前庭神经元在不同的行为背景。这些实验结果表明，在不同的行为环境下，中枢神经元携带的头部运动感觉信号的大小，甚至方向都是不同的。我们的结论是，中央前庭神经元产生的前庭感觉信号并不简单地与其他感觉和运动信号相结合，但取决于它们产生的行为背景。
The ostensible purpose of the vestibular sensory system is to inform the brain about the position and movement of the head. However, this sensory system is somewhat unusual in that sensory-motor integration occurs at the first stage of the central processing of vestibular signals. Many of the central, secondary vestibular neurons that receive direct inputs from the vestibular nerve also project directly to motoneurons and/or play an important role in a variety of motor behaviors. For example, lateral vestibulospinal tract neurons not only carry signals related to head movements, but are also phasically modulated during locomotion.'The secondary vestibular neurons that project to the extraocular motor nuclei carry signals related not only to ongoing head movements, but also signals related to eye position or smooth pursuit eye velocity, even in the absence of head m~ vements.~~~ In many instances the same central neuron serves as both a secondary sensory neuron and a constituent of an important premotor pathway. Thus, it is perhaps not surprising that many, if not most, of the neurons in the vestibular nuclei exhibit a complex combination of sensory and motor signals4 In this paper we briefly describe the results of several types of experiments in which single-unit recordings were obtained from squirrel monkey central secondary vestibular neurons in different behavioral contexts. The results of these experiments show that the magnitude, and even the direction of the head movement sensory signals carried by central neurons varies under different behavioral circumstances. We conclude that the vestibular sensory signals generated by central vestibular neurons are not simply combined with other sensory and motor signals, but are contingent on the behavioral context in which they are generated.