Sulfuryl chloride as an efficient initiator for the metal-free aerobic cross-dehydrogenative coupling reaction of tertiary amines.
Sulfuryl chloride as an efficient initiator for the metal-free aerobic cross-dehydrogenative coupling reaction of tertiary amines.
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DOI：
10.1021/ol500661t
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发表时间：
2014-04
期刊：
影响因子：
5.2
通讯作者：
Arata Tanoue;Woo‐Jin Yoo;S. Kobayashi
中科院分区：
文献类型：
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作者：
Arata Tanoue;Woo‐Jin Yoo;S. Kobayashi
在温和的好氧条件下，以一定量的硫酰氯（SO2Cl2）为催化剂，研究了叔胺的无金属交叉脱氢（CDC）反应。根据SO2Cl2的性质，可以认为该试剂作为自由基引发剂，通过自由基引发的自氧化机制诱导无金属的CDC反应。
A metal-free cross-dehydrogenative (CDC) reaction of tertiary amines was developed using a catalytic amount of sulfuryl chloride (SO2Cl2) under mild aerobic conditions. On the basis of the nature of SO2Cl2, it was assumed that the reagent acts as a radical initiator to induce the metal-free CDC reaction via a radical-initiated autoxidation mechanism.