Association between Fine Particulate Air Pollution and Daily Clinic Visits for Migraine in a Subtropical City: Taipei, Taiwan
Association between Fine Particulate Air Pollution and Daily Clinic Visits for Migraine in a Subtropical City: Taipei, Taiwan
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DOI：
10.3390/ijerph120504697
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发表时间：
2015-05-01
影响因子：
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通讯作者：
Yang, Chun-Yuh
中科院分区：
文献类型：
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作者：
Chen, Chih-Cheng;Tsai, Shang-Shyue;Yang, Chun-Yuh
本研究旨在确定台湾台北地区细颗粒物（PM2.5）水平与偏头痛的每日门诊就诊率之间是否存在相关性。从2006年至2011年期间，台北市的偏头痛和环境空气污染数据的日常诊所访问。使用病例交叉方法估计门诊就诊的比值比，控制天气变量、星期几、季节性和长期时间趋势。一般来说，在凉爽的日子里，PM2.5水平和偏头痛之间没有显着的联系。然而，在温暖的日子里，对于单一污染物模型（没有调整其他污染物），偏头痛的诊所就诊次数增加与PM2.5水平显著相关，四分位数范围（IQR）上升与偏头痛就诊次数增加13%（95%CI = 8%-19%）相关。在双污染物模型中，在温暖的日子里，包括二氧化硫（SO2）或臭氧（O-3）后，PM2.5仍然显着。这项研究提供的证据表明，在台湾台北，较高水平的PM2.5会增加偏头痛的诊所就诊风险。
This study was undertaken to determine whether there was an association between fine particle (PM2.5) levels and daily clinic visits for migraine in Taipei, Taiwan. Daily clinic visits for migraine and ambient air pollution data for Taipei were obtained for the period from 2006-2011. The odds ratio of clinic visits was estimated using a case-crossover approach, controlling for weather variables, day of the week, seasonality, and long-term time trends. Generally, no significant associations between PM2.5 levels and migraine visits were observed on cool days. On warm days, however, for the single pollutant model (without adjustment for other pollutants), increased clinic visits for migraine were significantly associated with PM2.5 levels, with an interquartile range (IQR) rise associated with a 13% (95% CI = 8%-19%) elevation in number of migraine visits. In bi-pollutant model, PM2.5 remained significant after the inclusion of sulfur dioxide (SO2) or ozone (O-3) on warm days. This study provides evidence that higher levels of PM2.5 increase the risk of clinic visits for migraine in Taipei, Taiwan.