Regional cerebral blood flow using quantitative MR angiography

Regional cerebral blood flow using quantitative MR angiography
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DOI:
10.3174/ajnr.a0582
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发表时间:
2007-09-01
影响因子:
3.5
通讯作者:
Charbel, F. T.
Charbel, F. T.
中科院分区:
医学2区
文献类型:
--
作者:
Zhao, M.;Amin-Hanjani, S.;Charbel, F. T.

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背景和目的:我们试图从定量磁共振血管造影(qMRA)获得局部脑血流量使用血管流量:材料和方法:在15个主要脑动脉的流速进行了测量,回顾性门控快速二维相位对比磁共振血管造影获得83名健康成人志愿者(年龄范围,24-74岁,平均42岁)。将脑动脉网划分为12个不同区域,根据15条脑动脉的实测流量计算出12个区域的流量。平均总颅血流量和平均总脑血流量分别为949 +/- 158 mL/min和695 +/- 113 ML/min。前循环和后循环的平均区域流量分别为483 +/- 87 mL/min和212 +/- 34 mL/min。得到了这11个区域的流量相对于其母区域的贡献。还计算了个体动脉和随年龄变化的区域的平均流量。女性组的平均流量显著低于男性组(P
BACKGROUND AND PURPOSE: We sought to derive regional cerebral blood flow using vessel flows from quantitative MR angiography (qMRA).MATERIALS AND METHODS: Flow rates in the 15 major cerebral arteries were measured on retrospectively gated fast 2D phase-contrast MR angiography obtained in 83 healthy adult volunteers (age range, 24-74 years; mean, 42 years). The arterial network of the brain was partitioned into 12 different regions, in which flows were calculated from the measured flows of the 15 cerebral arteries.RESULTS: The mean flows of the 15 arteries and the 12 regions were calculated. The mean total cranial flow and the mean total cerebral blood flow were 949 +/- 158 mL/min and 695 +/- 113 ML/min, respectively. The mean regional flows for the anterior and posterior circulation were 483 +/- 87 mL/min and 212 +/- 34 mL/min, respectively. The relative contributions of the flows in the 11 regions to their parent regions were obtained. The mean flows in the individual arteries and the regions with age were also calculated. The mean flows for the female group were significantly lower than those for the male group (P