ISOB: A Database of Indigenous Snake Species of Bangladesh with respective known venom composition.
ISOB: A Database of Indigenous Snake Species of Bangladesh with respective known venom composition.
复制标题
DOI：
10.6026/97320630011107
复制
发表时间：
2015
期刊：
影响因子：
1.9
通讯作者：
Reza MA
中科院分区：
文献类型：
--
作者：
Roly ZY;Hakim MA;Zahan AS;Hossain MM;Reza MA
尽管蛇毒在生物医学研究中具有重要意义，但目前世界上还没有一个结构良好的关于毒蛇及其毒液成分的数据库。从NCBI、PDB或公共数据库中搜索特定的毒液成分是很麻烦的，因为它们包含大量的数据条目。因此，我们创建了一个名为“ISOB”的数据库，这是一个可通过网络访问的唯一二级数据库，代表了第一个在线可用的生物信息学资源，显示了蛇的毒液成分。这个数据库提供了一个全面的概述78土著蛇物种涵盖补充的结构信息的相关个人可用的毒液蛋白的蛇的描述。我们坚信，该数据库将在生物信息学、环境研究、蛋白质组学、药物开发和合理药物设计领域做出重大贡献。该数据库可在http://www.snakebd.com/上免费获取
At present there is no well structured database available for the venomous snakes and venom composition of snakes in the world although venom has immense importance in biomedical research. Searching for a specific venom component from NCBI, PDB or public databases is troublesome, because they contain huge amount of data entries. Therefore, we created a database named “ISOB” which is a web accessible unique secondary database that represents the first online available bioinformatics resource showing venom composition of snakes. This database provides a comprehensive overview of seventy-eight indigenous snake species covering description of snakes supplemented with structural information of the relevant individual available venom proteins. We strongly believe that this database will contribute significantly in the field of bioinformatics, environmental research, proteomics, drug development and rationale drug designing. The database is freely available at http://www.snakebd.com/