Role of protein and amino acids in the pathophysiology and treatment of sarcopenia

Role of protein and amino acids in the pathophysiology and treatment of sarcopenia
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DOI:
10.1080/07315724.2005.10719455
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发表时间:
2005-04-01
影响因子:
3.5
通讯作者:
Volpi, E
Volpi, E
中科院分区:
医学4区
文献类型:
--
作者:
Dreyer, HC;Volpi, E

文献摘要

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肌肉减少症,即骨骼肌质量和功能随年龄增长而丧失,是一种多因素疾病,在数十年内缓慢发展,并成为老年人群残疾的重要因素。营养不良和肌肉对营养刺激的合成代谢反应的改变已被确定为可能显著导致肌肉减少症的潜在可预防因素。因此,营养干预可能有助于预防和治疗肌肉减少症。
Sarcopenia, the loss of skeletal muscle mass and function with aging, is a multifactorial condition that slowly develops over decades and becomes a significant contributor to disability in the older population. Malnutrition and alterations in the muscle anabolic response to nutritional stimuli have been identified as potentially preventable factors that may significantly contribute to sarcopenia. Thus, nutritional interventions may be useful for the prevention and treatment of sarcopenia.