CAND1 orchestrates CRLs through rock and roll.
CAND1 orchestrates CRLs through rock and roll.
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CAND1 通过摇滚乐来协调 CRL。
DOI：
10.1016/j.cell.2023.04.001
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发表时间：
2023
期刊：
影响因子：
64.5
通讯作者：
Zhao,Minglei
中科院分区：
文献类型：
--
作者：
Xie,Yuan;Zhao,Minglei
适当调节蛋白质的降解对细胞生理是必不可少的。在最新一期的《细胞》杂志上，Baek等人阐明了一类被称为CRL的泛素连接酶是如何通过一个关键的调节因子CAND1进行组装和拆卸的。
Proper regulation of protein degradation is essential for cell physiology. In the current issue ofCell, Baek et al. elucidated how a large class of ubiquitin ligase, known as CRL, is assembled and disassembled through a key regulator, CAND1.