Orofacial manifestations of adverse drug reactions: a review study.
Orofacial manifestations of adverse drug reactions: a review study.
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DOI：
10.15386/cjmed-748
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发表时间：
2018-01-01
期刊：
影响因子：
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通讯作者：
Bakhshi, Mahin
中科院分区：
文献类型：
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作者：
Bakhtiari, Sedigheh;Sehatpour, Marziye;Bakhshi, Mahin
背景：药物不良反应很常见，在口腔中可能有多种临床表现。方法：在这篇叙述性综述文章中，使用专业数据库如PubMed、PubMed Central、MEDLINE、EBSCO、Science Direct、Scopus和参考书，从2000-2016年使用MeSH术语查找相关文献：药物不良反应，药物引起的，药物相关的，口腔，口腔表现，牙齿，硬组织，软组织。唾液和唾液腺受累、软组织（粘膜）受累、硬组织受累和非特异性疾病（味觉障碍、口臭、神经病、运动障碍和感染）。大多数文章是关于药物对唾液腺功能的不良影响，这通常会导致唾液分泌减少。其他反应是不常见的，同时，副作用的双膦酸盐在牙槽骨增加，因为它的无限prescription.CONCLUSION：口腔卫生保健提供者应该熟悉这样的事件，因为他们将面对他们在实践中。
BACKGROUND: Adverse reaction to medication is common and may have a variety of clinical manifestations in the oral cavity. The present review paper aimed to describe adverse drug reactions (ADRs) which might be encountered by dental practitioners in every discipline.METHODS: In this narrative review article, the specialized databases such as PubMed, PubMed Central, MEDLINE, EBSCO, Science Direct, Scopus, and reference books from the years 2000-2016 were used to find relevant documents by using MeSH terms: Adverse Drug Reaction, Drug induced, Medication Related, Mouth, Oral Manifestation, Tooth, Hard Tissue, Soft Tissue.RESULTS: The data were categorized in 4 groups as follows: saliva and salivary glands involvement, soft tissue (mucosal) involvement, hard tissue involvement, and non specific conditions (taste disorders, halitosis, neuropathies, movement disturbances, and infection). Most articles were about the adverse effect of drugs on the function of salivary glands, which often cause a decrease in saliva secretion. Other reactions were less common; meanwhile, the side effect of bisphosphonate was increasing in the alveolar bone, because of its unlimited prescription.CONCLUSION: Oral health care providers should be familiar with such events, as they will be confronted with them in their practice.