The Relationships Between Cardiovascular Disease and Diabetes: Focus on Pathogenesis
The Relationships Between Cardiovascular Disease and Diabetes: Focus on Pathogenesis
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DOI：
10.1016/j.ecl.2013.09.007
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发表时间：
2014-03-01
影响因子：
4.5
通讯作者：
Fuster, Valentin
中科院分区：
文献类型：
--
作者：
Kovacic, Jason C.;Castellano, Jose M.;Fuster, Valentin
肥胖症和糖尿病正在全球范围内流行。在糖尿病引起的所有终末器官效应中，心血管系统特别容易受到这种疾病引起的生物扰动的影响，许多患者可能死于糖尿病相关的心血管并发症。在了解糖尿病血管和心脏的病理生物学方面已经取得了实质性进展。临床研究已经阐明了治疗这种疾病的心血管表现患者的最佳方法。本文综述了糖尿病与心血管系统的这些方面，大致分为糖尿病血管疾病，糖尿病心肌病，以及糖尿病心血管疾病患者的临床管理。
There is a looming global epidemic of obesity and diabetes. Of all the end-organ effects caused by diabetes, the cardiovascular system is particularly susceptible to the biologic perturbations caused by this disease, and many patients may die from diabetes-related cardiovascular complications. Substantial progress has been made in understanding the pathobiology of the diabetic vasculature and heart. Clinical studies have illuminated the optimal way to treat patients with cardiovascular manifestations of this disease. This article reviews these aspects of diabetes and the cardiovascular system, broadly classified into diabetic vascular disease, diabetic cardiomyopathy, and the clinical management of the diabetic cardiovascular disease patient.