Functional cardiac MR imaging with steady-state free precession (SSFP) significantly improves endocardial border delineation without contrast agents
Functional cardiac MR imaging with steady-state free precession (SSFP) significantly improves endocardial border delineation without contrast agents
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DOI：
10.1002/jmri.1195
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发表时间：
2001-10-01
影响因子：
4.4
通讯作者：
Fleck, E
中科院分区：
文献类型：
--
作者：
Thiele, H;Nagel, E;Fleck, E
临床常规使用的标准涡轮梯度回波磁共振技术（TFE）中血液和心肌之间的对比主要是由不饱和的流入血液引起的。即使没有流入效应，稳态自由进动 (SSFP) 也具有出色的对比度。使用 TFE 获取 45 名受试者的两个长轴投影中的心脏电影环，并与 SSFP 进行比较。为两个长轴视图中六个心肌节段的心内膜边界描绘分配视觉评分（范围 0 最差 - 3 最佳）。 TFE 的心内膜边界勾画评分为每节段 1.3 +/- 0.3，SSFP 的心内膜边界勾画评分为 2.4 +/- 0.3 (P < 0.0001)。 TFE 的血液信号强度/心肌信号强度分别为舒张末期 1.5 +/- 0.4 和收缩期 1.4 +/- 0.3，SSFP 分别为 3.5 +/- 1.1 和 3.2 +/- 1.3 (P < 0.0001)。 SSFP 使血液和心肌之间的对比度增加两倍以上，从而改善心内膜边界清晰度。这可以减少心脏容量和射血分数测定的可变性。 J.马格。共振。成像 2001；14：362-367。 (C) 2001 Wiley-Liss, Inc.
Contrast between blood and myocardium in standard turbo gradient echo MR techniques (TFE) used routinely in clinical practice is mainly caused by unsaturated inflowing blood. Steady-state free precession (SSFP) has excellent contrast even in the absence of inflow effects. In 45 subjects cardiac cine loops in two long axis projections were acquired using TFE and compared with SSFP. A visual score (range 0 worst - 3 best) was assigned for endocardial border delineation for six myocardial segments in two long axis views. Endocardial border delineation score for TFE was 1.3 +/- 0.3 per segment and 2.4 +/- 0.3 for SSFP (P < 0.0001). Signal intensity blood/signal intensity myocardium was 1.5 +/- 0.4 at enddiastole and 1.4 +/- 0.3 at systole for TFE and 3.5 +/- 1.1 and 3.2 +/- 1.3 for SSFP, respectively (P < 0.0001). SSFP increases contrast between blood and myocardium more than twofold, resulting in an improved endocardial border definition. This may reduce variability for the determination of cardiac volumes and ejection fraction. J. Magn. Reson. Imaging 2001;14: 362-367. (C) 2001 Wiley-Liss, Inc.