Relationship between periodontal disease and systemic health
Relationship between periodontal disease and systemic health
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DOI：
10.1034/j.1600-0757.2001.22250103.x
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发表时间：
2001-01-01
影响因子：
18.6
通讯作者：
Krall, EA
中科院分区：
文献类型：
--
作者：
Garcia, RI;Henshaw, MM;Krall, EA
在理解牙周病和全身健康之间的关系方面取得了非凡的进展。牙周炎是人类最古老和最常见的疾病之一，曾被普遍认为是衰老的必然结果。然而，随着时间的推移，我们了解到，并不是所有的人或所有的人都有同样的风险患牙周炎。越来越多的流行病学和实验工作有助于确定具体的风险因素和风险指标，使人们能够更好地了解是什么使个人更容易患牙周病(20)。这一新的认识越来越强调系统因素、疾病和条件在牙周病的病因和进展中可能发挥的重要作用。牙科也对行为因素在风险中发挥作用的程度有了更多的认识。这些调查的目的之一是使我们能够更好地识别易患牙周病的个体，以便更有效地预防和治疗这种疾病。现在人们普遍认识到，某些全身性疾病，如骨质疏松、糖尿病和免疫紊乱，可能会增加患牙周病的风险。然而，直到最近，人们对慢性口腔疾病对全身健康可能具有的作用的关注还较少。假设口腔疾病，如牙周感染，可能是重要医疗结果的风险因素或指标，代表了对因果关系以及口腔和全身关联的方向性的思维范式的转变()。
Extraordinary progress is being made in understanding the relationship between periodontal disease and systemic health. Periodontitis, one of the oldest and most common diseases of humans, was once generally believed to be an inevitable consequence of aging. However, we have learned over time that not all people, nor all populations, are at equal risk of developing periodontitis. An increasing body of epidemiological and experimental work has helped to identify specific risk factors and risk indicators, permitting better understanding of what makes an individual more susceptible to periodontal disease (20). This new knowledge gives increasing emphasis to the important role that systemic factors, diseases, and conditions may play in the causation and progression of periodontal disease. Dentistry has also become more cognizant of the extent to which behavioral factors play a role in risk. One goal of such investigations is that they may enable us to better identify individuals susceptible to periodontal disease in order to more effectively prevent and treat the disease.It is now becoming widely recognized that certain systemic diseases, such as osteoporosis, diabetes and immune disorders, may increase the risk for periodontal disease. However, until relatively recently, less attention has been devoted to exploring the role that chronic oral diseases may have on systemic health. The hypothesis that oral conditions, such as periodontal infections, may be risk factors or indicators for important medical outcomes represents a paradigm shift in thinking about causality and the directionality of oral and systemic associations (64).