P1 GENE-EXPRESSION IN DROSOPHILA LARVAL FAT-BODY - INDUCTION BY VARIOUS ECDYSTEROIDS
P1 GENE-EXPRESSION IN DROSOPHILA LARVAL FAT-BODY - INDUCTION BY VARIOUS ECDYSTEROIDS
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DOI：
10.1002/arch.940150105
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发表时间：
1990-01-01
影响因子：
2.2
通讯作者：
LAFONT, R
中科院分区：
文献类型：
--
作者：
SOMMEMARTIN, G;COLARDEAU, J;LAFONT, R
Using the developmental mutant ecd1, the biological activity of 20‐hydroxyecdysone (20E) and 20E metabolites 3‐dehydro‐20‐hydroxyecdysone (3D20E), 3‐epi‐20‐hydroxyecdysone (3D20E), 3‐epi‐20‐hydroxyecdysone‐3‐phosphate (20E′3P), 20,26‐dihydroxyecdysone (20,26E), and 20‐hydroxyecdysonoic acid (20Eoic) was tested for their ability to induce the transcription of the steroid‐inducible gene P1 in theDrosophilalarval fat body. 3D20E was the most efficient ecdysteroid in the initiation of P1 gene transcription therefore the formation of 3D20E and the 3‐epimer could not be regarded as an inactivation pathway inDrosophilalarvae. Formation of 20,26E and 20Eoic may be an inactivation pathway in this biological model.
