Hepatitis C (HCV) genotype and viral titer distribution among Argentinean hemophilic patients in the presence or absence of human immunodeficiency virus (HIV) co‐infection

Hepatitis C (HCV) genotype and viral titer distribution among Argentinean hemophilic patients in the presence or absence of human immunodeficiency virus (HIV) co‐infection
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存在或不存在人类免疫缺陷病毒(HIV)合并感染的阿根廷血友病患者中丙型肝炎(HCV)基因型和病毒滴度分布

DOI:
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发表时间:
1997
影响因子:
12.7
通讯作者:
D. Mosier
D. Mosier
中科院分区:
医学3区
文献类型:
--
作者:
G. Picchio;M. Nakatsuno;C. Boggiano;Rebecca Sabbe;M. Corti;J. Daruich;R. PÉREZ‐BIANCO;M. Tezanos;Robert Kokka;J. Wilber;D. Mosier

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丙型肝炎(HCV)感染在接受非灭活因子浓缩治疗的血友病患者中很常见。HCV基因型和病毒载量都被认为是疾病进展和治疗结果的重要预后标志物。此外,人类免疫缺陷病毒(HIV)的共感染与HCV复制水平增加和肝功能衰竭的风险增加有关。因此,HCV基因型、病毒载量和HIV共感染是HCV感染的重要因素。
Hepatits C (HCV) infection is frequent among hemophilic patients treated with non‐inactivated factor‐concentrates. Both HCV genotype and viral load have been suggested to be important prognostic markers of disease progression and treatment outcome. In addition, co‐infection with the human immunodeficiency virus (HIV) has been associated with increased level of HCV replication and higher risk of developing liver failure. Thus, HCV genotype, viral load, and HIV co‐infection are important factors in HCV infection.
DOI: --
发表时间: 1993
期刊: Journal of acquired immune deficiency syndromes
影响因子: --
作者:
Eyster,ME;Diamondstone,LS;Lien,JM;Ehmann,WC;Quan,S;Goedert,JJ
通讯作者: Goedert,JJ