Problem drinking and medication adherence among persons with HIV infection
Problem drinking and medication adherence among persons with HIV infection
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DOI：
10.1046/j.1525-1497.2001.00122.x
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发表时间：
2001-02-01
影响因子：
5.7
通讯作者：
Conigliaro, J
中科院分区：
文献类型：
--
作者：
Cook, RL;Sereika, SM;Conigliaro, J
目的：为探讨HIV感染者饮酒与服药依从性的关系，设计：横断面调查，地点/对象：1997 - 12/1998 - 02在2所门诊就诊的212例HN感染者。19%的受试者报告在前一个月有饮酒问题，14%的受试者在前24小时内错过了至少一剂药物，30%的人在前一周没有按时服药。问题饮酒者报告漏服药物的可能性略高（17%对12%，P = 0.38），报告服药时间表的可能性明显更高（45%对26%，P = 0.02）。在饮酒亚型中，不按时服药与大量饮酒（高数量/频率）显著相关（校正比值比[OR]，4.70：95%置信区间[95%CI]，1.49至14.84; P
OBJECTIVE: To examine the relation between problem drinking and medication adherence among persons with HIV infection,DESIGN: Cross-sectional survey.SETTING/PARTICIPANTS: Two hundred twelve persons with HN infection who visited 2 outpatient clinics between December 1997 and February 1998.MEASUREMENTS AND MAIN RESULTS: Nineteen percent of subjects reported problem drinking during the previous month, 14% missed at least 1 dose of medication within the previous 24 hours, and 30% did not take their medications as scheduled during the previous week. Problem drinkers were slightly more likely to report a missed dose (17% vs 12%, P =.38] and significantly more likely to report taking medicines off schedule (45% vs 26%, P =.02). Among drinking subtypes, taking medications off schedule was significantly associated with both heavy drinking (high quantity/frequency) (adjusted odds ratio [OR], 4.70: 95% confidence interval [95% CI], 1.49 to 14.84; P