Prediction of the true IOL position
Prediction of the true IOL position
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DOI：
10.1136/bjophthalmol-2016-309543
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发表时间：
2017-10-01
影响因子：
4.1
通讯作者：
Findl, Oliver
中科院分区：
文献类型：
--
作者：
Norrby, Sverker;Bergman, Rolf;Findl, Oliver
Purpose to develop algorithms for preoperative estimation of the true postoperative intraocular透镜（IOL）position to be used for IOL power calculation.Setting Moorfields Eye Hospital NHS Foundation Trust，伦敦，UK.方法50例患者随机植入3件式IOL模型在一只眼睛和1件式模型在另一只眼睛。术前使用IOLMaster测量眼轴长度、前房深度和平均角膜半径。用ACMaster测量透镜厚度和角膜宽度。使用ACMaster测量术后IOL位置。结果偏最小二乘（PLS）回归分析显示，年龄、屈光度、角膜宽度、透镜厚度和角膜半径对术后人工晶状体前表面位置无显著影响，而眼轴长度和前房深度对术后人工晶状体前表面位置有显著影响。确定了植入的两种模型与上述预测因子的回归关系。令人惊讶的是，结果表明，后IOL表面的位置可以通过对两种模型均有效的单一回归关系来描述。所有关系预测人工晶状体位置的残差标准差约为0.17mm。结论获得了准确的人工晶状体位置关系。除了IOL屈光度计算所需的眼轴长度和角膜半径外，仅需测量术前前房深度。
Purpose To develop algorithms for preoperative estimation of the true postoperative intraocular lens (IOL) position to be used for IOL power calculation.Setting Moorfields Eye Hospital NHS Foundation Trust, London, UK.Methods Fifty patients were implanted randomly with a 3-piece IOL model in one eye and a 1-piece model in the other eye. Preoperatively, the IOLMaster was used to determine axial length, anterior chamber depth and mean corneal radius. Lens thickness and corneal width were measured with the ACMaster. Postoperative IOL position was measured with the ACMaster. Partial least squares (PLS) regression analysis of IOL position in terms of preoperative parameters was performed with a commercially available software package.Results The PLS regression analysis showed that age, refraction, corneal width, lens thickness and corneal radius are not significant predictors of postoperative position of the anterior IOL surface, while axial length and in particular anterior chamber depth are. Regression relationships in terms of the above-mentioned predictors were determined for the two models implanted. Surprisingly, it turned out that the position of the posterior IOL surface could be described by a single regression relationship valid for both models. The residual SD for prediction of IOL position was about 0.17 mm for all relationships.Conclusions Accurate relationships to determine the true postoperative IOL position were obtained. In addition to axial length and corneal radius, which are required for the IOL power calculation as such, they require measurement of preoperative anterior chamber depth only.