Sleep Disturbances Among Young Patients with IBD in Israel
Sleep Disturbances Among Young Patients with IBD in Israel
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以色列年轻 IBD 患者的睡眠障碍
DOI：
10.1097/01.mpg.0000256257.53363.40
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发表时间：
2006
影响因子：
2.9
通讯作者：
Y. Bujanover
中科院分区：
文献类型：
--
作者：
V. Nachmias;A. Sheinberg;B. Weiss;A. Fradkin;Y. Bujanover
目的：这项前瞻性调查旨在研究炎症性肠病（IBD）年轻患者睡眠障碍的患病率，并调查疾病特征和活动对这些患者睡眠模式的影响。方法：从2006年1月到6月，来自以色列Safra儿童医院儿科胃肠科的41名连续IBD患者，采用简易睡眠问卷调查失眠、白天过度嗜睡和其他睡眠特征。在调查时记录患者的人口统计学和临床数据。结果：41例患者（50.2%为女性，年龄16.9±4.0岁）中，22例（54%）有睡眠障碍，10例（24%）有中度睡眠障碍，12例（29%）有重度睡眠障碍。最常见的睡眠障碍是早晨醒来时疲劳（75.6%），睡眠中醒来（53.6%）和慢性不明原因的疲劳（39%）。只有一名患者使用了安眠药。睡眠障碍与疾病类型，疾病活动，医疗，人体测量措施，年龄和性别的patients.Conclusions：这项研究是第一次评估IBD患者的睡眠模式和障碍之间没有相关性。中度和重度睡眠障碍在IBD患者中很常见，然而，在这项小型研究中，未证明与疾病特征和药物治疗相关。需要更大规模的对照研究，并通过多导睡眠图评估IBD患者的睡眠模式。
Objective: This prospective survey was conducted to examine the prevalence of sleep disturbances among young patients with inflammatory bowel disease (IBD), and to investigate the influence of disease characteristics and activity on sleep patterns in these patients.Methods: From January through June 2006, 41 consecutive IBD patients, from the Pediatric Gastroentnrology division at Safra Children's Hospital in Israel, were investigated using Mini-Sleep Questionnaire to detect insomnia, excessive daytime sleepiness and other sleep characteristics. Demographic and clinical data of the patients were recorded at the time of the survey. Statistical analysis included Analysis of Variance, Kruskal-Wallis Analysis of Variance, and Pearson's Chi-Square Test.Results: Out of 41 patients (50.2% females, age 16.9±4.0 years), 22 (54%) had sleep disturbances; Ten patients (24%) had moderate sleep disturbance score, and 12 patients (29%) had severe sleep disturbance score. The most frequent sleep disturbances were morning fatigue on awakening (75.6%), waking up during sleep (53.6%) and chronic unexplained fatigue (39%). Only one patient used sleep medication. No correlation was found between sleep disturbances and disease type, disease activity, medical treatment, anthropometric measures, age and gender of the patients.Conclusions: This study is the first to evaluate sleep patterns and disturbances in IBD patients. Moderate and severe sleep disturbances are frequent among IBD patients, however, in this small study, no correlation to disease characteristics and medical therapy was demonstrated. Larger scale controlled studies, and evaluation of sleep patterns in IBD patients by polysomnography, are needed.