Oxygen tension in human tumors: in vivo mapping using CT-guided probes.
Oxygen tension in human tumors: in vivo mapping using CT-guided probes.
复制标题
人类肿瘤中的氧张力：使用 CT 引导探针进行体内绘图。
作者：
R. Gatenby;L. Coia;M. Richter;H. Katz;P. Moldofsky;P. Engstrom;D. Brown;R. Brookland;G. Broder
氧在肿瘤对治疗的反应中所起的作用已经被研究了几十年。我们描述了一种利用计算机断层扫描引导探针在体内测量肿瘤中氧含量的技术。在对16个肿瘤的评估中，发现氧分压明显低于周围组织，且并非随机变化。这项技术使得构建详细的肿瘤氧含量水平图谱成为可能。
The role of oxygen in tumor response to therapy has been studied for several decades. We describe a technique that allows in vivo measurement of oxygen in tumors using computed tomography to guide probes. In the evaluation of 16 tumors, oxygen tensions were found to be substantially lower than surrounding tissue and varied nonrandomly. This technique has allowed construction of detailed tumor oxygen level maps.