Increased incidence of cholecystectomy related to gallbladder disease in France: Analysis of 807,307 cholecystectomy procedures over a period of seven years
Increased incidence of cholecystectomy related to gallbladder disease in France: Analysis of 807,307 cholecystectomy procedures over a period of seven years
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DOI：
10.1016/j.jviscsurg.2018.12.003
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发表时间：
2019-06-01
影响因子：
2.1
通讯作者：
Chazard, E.
中科院分区：
文献类型：
--
作者：
Bray, F.;Balcaen, T.;Chazard, E.
目的：胆结石是入院最常见的腹部原因之一。本研究的目的是分析 2008 年至 2014 年法国因胆囊相关疾病接受胆囊切除术的患者的趋势和结果。 患者和方法：我们使用从法国全国医院出院数据库 (PMSI) 提取的数据进行了一项基于人群的回顾性队列研究。我们纳入了 2008 年 1 月至 2014 年 12 月期间所有因胆囊疾病接受胆囊切除术的患者。分析了患者的人口统计、初步诊断、手术类型、住院时间 (LOS)、入住重症监护病房、出院处置、并发症和院内死亡率。结果：总体而言，在研究期间，法国进行了 807,307 例胆囊切除术，全国发病率自每 100,000 名居民为 167.5 (95% CI [166.5; 168.5]) 至 182.6 (95% CI [181.6; 183.6])。女性占手术的 66.5% (P < 0.001)。女性的平均年龄低于男性：52.1 岁 vs 60.2 岁（P < 0.001）。腹腔镜胆囊切除术的比例从2008年的90%显着上升到2014年的94%（P < 0.001）。平均住院 LOS 从 2008 年的 6.5 天显着下降至 2014 年的 4.7 天（P < 0.001）。最常见的并发症类型是腹腔镜手术的腹腔内并发症（23.1%）（95% CI [22.7; 23.5]），院内死亡率随着时间的推移显着下降，从 2008 年的 0.45% 降至 2014 年的 0.38%（P < 0.005）。 结论：我们的结果表明，全国胆囊疾病相关胆囊切除术的发生率有所增加2008 年至 2014 年。(C) 2018 Elsevier Masson SAS。版权所有。
Purpose: Gallstones are one of the most common abdominal reasons for admission to hospital. The aim of this study was to analyze trends and outcomes in patients undergoing cholecystectomy with gallbladder related disease in France from 2008 to 2014.Patients and Methods: We carried out a population-based, retrospective cohort study using data extracted from the French nationwide hospital discharge database (PMSI). We included all patients having a cholecystectomy related to gallbladder disease from January 2008 to December 2014. Patients' demographics, primary diagnosis, procedure type, length of stay (LOS), admission in an intensive care unit, discharge disposition, complications, and in-hospital mortality were analyzed.Results: Overall, 807,307 cholecystectomies were performed in France over the study period, with an increase in the national incidence rate from 167.5 (95% CI [166.5; 168.5]) to 182.6 (95% CI [181.6; 183.6]) per 100,000 inhabitants. Females accounted for 66.5% of procedures (P < 0.001). The mean age was lower for females than for males: 52.1 versus 60.2 (P < 0.001). The ratio of laparoscopic cholecystectomy significantly increased from 90% in 2008 to 94% in 2014 (P < 0.001). Average inpatient LOS decreased significantly from 6.5 days in 2008 to 4.7 days in 2014 (P < 0.001). Most common complication type was intra-abdominal (23.1%) for laparoscopic procedure (95% CI [22.7; 23.5]), and in-hospital mortality significantly decreased over time from 0.45% in 2008 to 0.38% in 2014 (P < 0.005).Conclusion: Our results showed that the national incidence rate of cholecystectomy related to gallbladder disease increased from 2008 to 2014. (C) 2018 Elsevier Masson SAS. All rights reserved.