The health-related quality of life of people living with HIV/AIDS
The health-related quality of life of people living with HIV/AIDS
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DOI：
10.1080/09638280410001662932
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发表时间：
2004-03-18
影响因子：
2.2
通讯作者：
Tinise, X
中科院分区：
文献类型：
--
作者：
Hughes, J;Jelsma, J;Tinise, X
目的：南非艾滋病毒/艾滋病感染者（PLWA）的患病率估计约占总人口的14.2%。在没有抗逆转录病毒治疗的情况下，PLWA可能会经历功能的稳步下降，因为他们的免疫系统越来越受到损害。然而，有有限的信息，以确定潜在的作用，康复干预措施的管理PLWA在一个资源贫乏的community.Subjects：受试者被招募从人口的艾滋病毒/艾滋病诊所的受益人由无国界医生组织，提供抗逆转录病毒治疗PLWA在一个资源贫乏的社区。这些受试者属于世卫组织疾病3期或4期和/或CD 4计数低于200，在参加抗逆转录病毒方案后和开始治疗前接受了访谈。因此，他们尚未接受抗逆转录病毒疗法。对照组由一个社区样本随机选择从同一地区，谁是在相同的年龄范围。方法：由于所有参与者科萨语发言，科萨版本的EQ-5D测量HRQoL被利用。分析：使用Mann-Whitney U检验确定EQ-5D和视觉焦虑健康状况量表评分的5个不同领域的应答排序是否存在差异。结果：实验组123例，对照组108例。在活动领域，30.9%的受试者报告了一些或严重的问题，而对照组为14.8%（p
Purpose: The prevalence of people living with HIV/ AIDS (PLWA) in South Africa is estimated to be approximately 14.2% of the total population. In the absence of anti-retroviral therapy, PLWA are likely to experience a steady decline in function, as their immune systems become increasingly compromised. However, there is limited information available to determine the potential role of rehabilitation interventions in the management of PLWA in a resource-poor community.Subjects: Subjects were recruited from the population of beneficiaries of HIV/ AIDS clinics run by Medecins Sans Frontieres, which provides anti-retroviral therapy to PLWA within a resource poor community. The subjects, who were either in WHO Stage 3 or 4 of the disease and/or had a CD4 count of less than 200, were interviewed after enrolment on the anti-retroviral programme and before treatment was initiated. They were therefore not yet receiving anti-retroviral therapy. The control group consisted of a community sample randomly selected from the same area and who were in the same age range.Methods: As all participants were Xhosa speaking, the Xhosa version of the EQ-5D measure of HRQoL was utilized. Analysis: The Mann - Whitney U-test was used to determine whether there was a difference in the rank ordering of responses to the five different domains of the EQ-5D and the Visual Analogue Scale of Health Status scores. Results: There were 123 and 108 subjects in the experimental and control groups, respectively. In the domain of mobility 30.9% of the subjects reported some or severe problems, compared to 14.8% of the control group (p