Metabolic Syndrome Does Not Detect Metabolic Risk in African Men Living in the US
Metabolic Syndrome Does Not Detect Metabolic Risk in African Men Living in the US
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DOI：
10.2337/dc11-1055
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发表时间：
2011-10-01
期刊：
影响因子：
16.2
通讯作者：
Sumner, Anne E.
中科院分区：
文献类型：
--
作者：
Ukegbu, Ugochi J.;Castillo, Darleen C.;Sumner, Anne E.
目的-比较移民美国的非洲人和非裔美国人的代谢风险和代谢综合征 (MetSyn) 患病率。如果 MetSyn 是心脏代谢风险的有效预测因子，那么代谢风险状况较差的群体的 MetSyn 发生率将会更高。 研究设计和方法 - 对 95 名男性（39 名非洲人、56 名非裔美国人，年龄 38 +/- 6 岁 [平均值 +/- SDI]）进行了横断面分析。葡萄糖耐量通过口服葡萄糖耐量试验确定，内脏脂肪组织（VAT）通过计算机断层扫描确定，MetSyn通过五个因素中的三个确定：中心性肥胖、高甘油三酯血症、低水平HDL胆固醇、高血压和空腹高血糖。 结果-MetSyn在非洲人和非裔美国人中的患病率相似（10% vs. 13%，P = 0.74），但高血压、非洲人的血糖（空腹和 2 小时血糖）和增值税较高。 结论：非洲移民的代谢状况比非裔美国人差，但 MetSyn 患病率相似。因此，MetSyn 可能会低估非洲人的代谢风险。
OBJECTIVE-Metabolic risk and metabolic syndrome (MetSyn) prevalence were compared in Africans who immigrated to the U.S. and African Americans. If MetSyn were an effective predictor of cardiometabolic risk, then the group with a worse metabolic risk profile would have a higher rate of MetSyn.RESEARCH DESIGN AND METHODS-Cross-sectional analyses were performed on 95 men (39 Africans, 56 African Americans, age 38 +/- 6 years [mean +/- SDI). Glucose tolerance was determined by oral glucose tolerance test, visceral adipose tissue (VAT) was determined by computerized tomography, and MetSyn was determined by the presence of three of Five factors: central obesity, hypertriglyceridemia, low levels of HDL cholesterol, hypertension, and fasting hyperglycemia.RESULTS-MetSyn prevalence was similar in Africans and African Americans (10 vs. 13%, P = 0.74), but hypertension, glycemia (fasting and 2-h glucose), and VAT were higher in Africans.CONCLUSIONS-African immigrants have a worse metabolic profile than African Americans but a similar prevalence of MetSyn. Therefore, MetSyn may underpredict metabolic risk in Africans.