[Studies on the chemical constituents of Smilax glabra].
[Studies on the chemical constituents of Smilax glabra].
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DOI：
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发表时间：
1998-11
期刊：
影响因子：
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通讯作者：
Y. Yi;Z. Cao;D. Yang;Y. Cao;Y. Wu;S. Zhao
中科院分区：
文献类型：
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作者：
Y. Yi;Z. Cao;D. Yang;Y. Cao;Y. Wu;S. Zhao
土豆是一种著名的中药，临床上用于预防钩端螺旋体病、治疗梅毒、急性细菌性痢疾等，其提取物具有抗肿瘤和抗动脉粥样硬化的活性。从土豆根中分离得到一个新的异黄酮类化合物7，6‘-二羟基-3’-甲氧基异黄酮类化合物(1)和两个已知化合物紫杉酯(2)和落新妇苷(3)。通过包括2D核磁共振技术在内的波谱方法对其结构进行了鉴定。
Smilax glabra is a well-known traditional Chinese medicine which has been used clinically to prevent leptospirosis, to treat syphilis, and acute bacterial dysentery, etc. Its extracts showed anti-tumor and anti-atherosclerosis activity. A new isoflavone, 7,6'-dihydroxy 3'-methoxy isoflavone (1), along with two known compounds taxifolin (2) and astilbin (3), have been isolated from the roots of Smilax glabra. The structures were elucidated by spectroscopic methods including 2DNMR techniques.