Cytoskeletal events in growth cone steering
Cytoskeletal events in growth cone steering
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DOI：
10.1016/0959-4388(94)90030-2
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发表时间：
1994-01-01
影响因子：
5.7
通讯作者：
O'Connor, Timothy P.
中科院分区：
文献类型：
--
作者：
Bentley, David;O'Connor, Timothy P.
定向神经生长依赖于生长锥响应于与指导信息的接触而重新定向其迁移方向的能力。最近的观察已经将注意力转向肌动蛋白分布和浓度在将局部外周信号传递到生长锥的中心元件，特别是微管中的作用。
Oriented neural outgrowth is dependent upon the capability of growth cones to reorient the direction of their migration in response to contact with guidance information. Recent observations have directed attention toward the role of actin distribution and concentration in transmitting localized peripheral signals to central elements of the growth cone, particularly microtubules.