Effect of cataract surgery on vision-related quality of life among cataract patients with high myopia: a prospective, case-control observational study
Effect of cataract surgery on vision-related quality of life among cataract patients with high myopia: a prospective, case-control observational study
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白内障手术对高度近视白内障患者视力相关生活质量的影响：一项前瞻性病例对照观察研究
DOI：
10.1038/s41433-021-01697-6
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发表时间：
2021-07-21
期刊：
影响因子：
3.9
通讯作者：
Wu，Mingxing
中科院分区：
文献类型：
--
作者：
Tan，Yehui;Liu，Liangping;Wu，Mingxing
目的探讨白内障超声乳化手术对高度近视（HM）白内障患者视觉相关生活质量（VR-QOL）的影响。方法90例HM患者（HM组，平均年龄62.9 [9.7]岁）和90例年龄匹配的正常眼轴（ALs）患者（对照组）接受超声乳化手术。术前和术后6个月使用25项国家眼科研究所视功能问卷（NEI-VFQ-25）评估VR-QOL。结果HM组术后最佳矫正视力（BCVA）提高≥ 0.2logMAR单位者78例（86.7%），高于对照组的61.1%（P < 0.001）。尽管HM组术前NEI-VFQ-25综合评分低于对照组，术后综合评分（65.8 ± 4.7 [95%CI] vs77.3 ± 3.8，P < 0.001）两组间差异无统计学意义（87.5 ± 2.6vs90.4 ± 1.6，P = 0.126，HM组综合评分及7个分量表评分的变化均大于对照组（均P< 0.05）。在HM组中，患者年龄与综合评分的变化呈负相关（r =-0.019，P = 0.860），而在对照组中则不然（r =-0.235，P = 0.026）。两组患者术前BCVA（logMAR）与综合评分的变化呈正相关（r分别为0.796和0.714，P均< 0.001）。其改善程度大于正常AL患者。
ObjectivesTo evaluate the effect of cataract surgery on vision-related quality of life (VR-QOL) in cataract patients with high myopia (HM).MethodsIn this prospective study, 90 patients with bilateral HM (HM group, mean [SD] age, 62.9 [9.7] years) and 90 age-matched patients with normal axial lengths (ALs) (control group) who underwent phacoemulsification surgery were consecutively included. The VR-QOL was evaluated using the 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ-25) preoperatively and 6 months postoperatively. During the same periods, the best-corrected visual acuity (BCVA) was recorded.ResultsPostoperatively, the BCVA improved significantly in the HM group, with 78 patients (86.7%) achieving improvements ≥0.2 logMAR units, higher than that in the control group (61.1%,P< 0.001). Although the preoperative NEI-VFQ-25 composite score was lower in the HM group than in the control group (65.8 ± 4.7 [95% CI] versus 77.3 ± 3.8,P< 0.001), the postoperative composite score was not significantly different between the two groups (87.5 ± 2.6 versus 90.4 ± 1.6,P= 0.126); changes in composite score and scores of 7 subscales were greater in the HM group than in the control group (P< 0.05 for all). In the HM group, but not in the control group (r = −0.019,P= 0.860), patient age was negatively associated with the change in composite score (r = −0.235,P= 0.026). Preoperative BCVA (logMAR) was positively associated with changes in composite score for both groups (r = 0.796 and 0.714, respectively,P< 0.001 for both).ConclusionsVR-QOL is significantly impaired in cataract patients with HM and is remarkably improved by cataract surgery. The improvement is greater than that in normal AL cases.