Barriers to and facilitators of HIV-positive patients' adherence to antiretroviral treatment regimens
Barriers to and facilitators of HIV-positive patients' adherence to antiretroviral treatment regimens
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DOI：
10.1089/108729100317948
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发表时间：
2000-03-01
影响因子：
4.9
通讯作者：
Roberts, KJ
中科院分区：
文献类型：
--
作者：
Roberts, KJ
艾滋病毒阳性患者必须严格遵守抗逆转录病毒治疗方案，以使药物正常发挥作用。然而，很少有人知道患者在坚持治疗方案时面临的障碍，或者什么（如果有的话）能帮助患者坚持下去。该项目的目标是从艾滋病毒阳性患者自己的角度描述他们在坚持抗逆转录病毒治疗方案时面临的障碍，以及他们用来最大限度地坚持治疗的策略。五个主要障碍（健忘、社会/物理环境、治疗方案的复杂性、药物副作用和患者知识不足）和六个主要促进因素（机械设备、“做出承诺”、“常规化”、健康信念、社会支持和专业支持）从数据中浮现出来。患者可以通过接受更好的健康教育来克服其中的一些障碍，这些教育包括坚持治疗的必要性，对他们的努力提供专业和世俗的支持，以及使用闹钟和医疗设备等机械设备。然而，其他障碍，如药物的复杂性，突出了简化抗逆转录病毒治疗方案的必要性。
HIV-positive patients must strictly adhere to antiretroviral regimens for the medications to work properly. Little, however, is known about the obstacles that patients face in adhering to the regimens or what, if anything, helps patients to adhere. The goals of the project were to describe, from HIV-positive patients' own perspectives, the barriers they face in adhering to antiretroviral regimens and the strategies they use to maximize their adherence. Five main barriers (forgetfulness, social/physical environment, complexity of the regimens, medication side effects, and inadequate patient knowledge) to adherence and six main facilitators (mechanical devices, "making a commitment," "routinizing," health beliefs, social support, and professional support) emerged from the data. Patients may overcome some of these barriers by receiving better health education about the need for adherence, professional and lay support for their efforts, and mechanical devices such as alarm clocks and medi-sets. Other barriers, however, such as the complexity of the medications, highlight the need for simplified antiretroviral regimens.