Capturing the microbial volatilome: an oft overlooked 'ome'
Capturing the microbial volatilome: an oft overlooked 'ome'
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捕获微生物挥发组：一个经常被忽视的“组”
DOI：
10.1016/j.tim.2021.12.004
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发表时间：
2022
影响因子：
15.9
通讯作者：
Tfaily, Malak M.
中科院分区：
文献类型：
--
作者：
Meredith, Laura K.;Tfaily, Malak M.
在微生物群落产生的各种代谢物中，有些是挥发性的。挥发性有机化合物（VOCs）是微生物作为代谢底物和产物以及作为信号分子进行剧烈循环的物质。然而，目前的微生物代谢组学研究主要集中在非挥发性代谢物和忽视挥发性有机化合物，因此代表了代谢组学的缺失的组成部分。VOC检测的进步现在允许同时观察构成微生物系统“挥发组”的众多VOC。我们提出了一个整合和推进VOC和其他“组学”方法的路线图，并强调了实时VOC测量的潜力，以帮助克服离散“组学”采样的局限性。在代谢组学中包括挥发性代谢物，无论是在概念上还是在实践中，都将建立对生态群落中微生物过程的更全面的理解。
Among the diverse metabolites produced by microbial communities, some are volatile. Volatile organic compounds (VOCs) are vigorously cycled by microbes as metabolic substrates and products and as signaling molecules. Yet, current microbial metabolomic studies predominantly focus on nonvolatile metabolites and overlook VOCs, which therefore represent a missing component of the metabolome. Advances in VOC detection now allow simultaneous observation of the numerous VOCs constituting the ‘volatilome' of microbial systems. We present a roadmap for integrating and advancing VOC and other ‘omics approaches and highlight the potential for realtime VOC measurements to help overcome limitations in discrete ‘omics sampling. Including volatile metabolites in metabolomics, both conceptually and in practice, will build a more comprehensive understanding of microbial processes across ecological communities.