Role of osteal macrophages in bone metabolism.

Role of osteal macrophages in bone metabolism.
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DOI:
10.4132/jptm.2015.02.02
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发表时间:
2015-03
影响因子:
2.4
通讯作者:
Cho SW
Cho SW
中科院分区:
其他
文献类型:
--
作者:
Cho SW

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巨噬细胞已被证明在各种病理生理中具有多种功能,特别是在抗炎和再生活性方面。近年来,骨髓巨噬细胞在骨骼发育、重塑和组织修复过程中的新功能得到了广泛的研究。这篇综述讨论了目前关于骨巨噬细胞在骨建模、重塑和骨折愈合过程中的作用的证据。
Macrophages have been shown to have pleiotropic functions in various pathophysiologies, especially in terms of anti-inflammatory and regenerative activity. Recently, the novel functions of bone marrow resident macrophages (called osteal macrophages) were intensively studied in bone development, remodeling and tissue repair processes. This review discusses the current evidence for a role of osteal macrophages in bone modeling, remodeling, and fracture healing processes.