Geographic linkage and variation in cryptosporidium hominis
Geographic linkage and variation in cryptosporidium hominis
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DOI：
10.3201/eid1403.071320
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发表时间：
2008-03-01
影响因子：
11.8
通讯作者：
Hunter, Paul
中科院分区：
文献类型：
--
作者：
Chalmers, Rachel M.;Hadfield, Stephen J.;Hunter, Paul
英国人隐孢子虫分离株先前在多个位点显示轻微的PCR片段长度多态性。为了进一步调查传播，我们进行了一项病例对照研究，并对115株分离株的GP60位点进行了测序。共鉴定出9种亚型，以IbA10G2为主。非IbA10G2亚型与最近在欧洲以外的旅行密切相关。
UK Cryptosporidium hominis isolates have previously shown slight PCR fragment length polymorphism at multiple loci. To further investigate transmission, we conducted a case-control study and sequenced the GP60 locus from 115 isolates. Nine subtypes were identified; IbA10G2 predominated. Having a non-IbA10G2 subtype was significantly linked to recent travel outside Europe.