Adherence to CPAP therapy improves quality of life and reduces symptoms among obstructive sleep apnea syndrome patients
Adherence to CPAP therapy improves quality of life and reduces symptoms among obstructive sleep apnea syndrome patients
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DOI：
10.1007/s11325-011-0543-8
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发表时间：
2012-06-01
影响因子：
2.5
通讯作者：
Behrakis, Panagiotis
中科院分区：
文献类型：
--
作者：
Avlonitou, Eirini;Kapsimalis, Fotis;Behrakis, Panagiotis
为评价阻塞性睡眠呼吸暂停综合征（OSAS）患者持续气道正压通气（CPAP）治疗6个月后的生活质量和症状，对50例经多导睡眠图确诊的OSAS患者（男41例，女9例）进行CPAP治疗6个月。他们的症状和健康相关的生活质量进行了评估，通过管理一个验证和翻译版本的睡眠呼吸暂停生活质量指数（SAQLI）。使用埃普沃思嗜睡量表（ESS）和电子监测每晚睡眠的CPAP使用情况来测量嗜睡程度，平均每晚使用CPAP 4.5 +/- 0.5小时。CPAP治疗前后生活质量指标的比较显示SAQLI总分有所改善（CPAP后3.8 ± 0.9 vs. 5.8 ± 0.8，p < 0.01），日常功能（4.2 +/- 1.4 vs. 6.0 +/- 0.9，p < 0.01），社会互动（4.8 ± 1.3 vs.6.3 ± 0.7，p < 0.01），情绪功能（4.4 +/- 1.4 vs. 5.7 +/- 1.0，p < 0.01），症状（1.6 +/- 0.8 vs. 5.8 +/- 1.2，p < 0.01），ESS（13.7 +/- 6.5 vs. 3.9 +/- 3.8，p < 0.01）。关于患者的症状，观察到“观看奇观时困倦”（96%）、“阅读”（95%）、“进行谈话”（95%）、“驾驶”（92.9%）、“睡眠不安”（87.8%）和“每晚排尿超过一次”（84.8%）的改善。观察到较小的改善报告“醒来时口干”（36.1%），“过度疲劳”（54.5%），和“减少能源”（55.3%）。我们的结论是，OSAS患者坚持夜间CPAP治疗显示出显着改善他们的生活质量，白天嗜睡，并与CPAP治疗6个月后的其他症状。
The aim of the study was to asses quality of life and symptoms of obstructive sleep apnea syndrome (OSAS) patients after adhering to 6 months of continuous positive airway pressure (CPAP) treatment.A group of 50 patients (41 men and 9 women) were diagnosed by polysomnography and treated with CPAP therapy for 6 months. Their symptoms and health-related quality of life were assessed by administering a validated and translated version of the sleep apnea quality of life index (SAQLI). Sleepiness was measured using the Epworth Sleepiness Scale (ESS) and through electronic monitoring of CPAP usage per night of sleep.Mean CPAP usage was 4.5 +/- 0.5 h per night. Comparisons between quality of life indexes before and after CPAP treatment showed an improvement in the total SAQLI score (3.8 +/- 0.9 vs. 5.8 +/- 0.8 after CPAP, p < 0.01), in daily functioning (4.2 +/- 1.4 vs. 6.0 +/- 0.9, p < 0.01), social interactions (4.8 +/- 1.3 vs.6.3 +/- 0.7, p < 0.01), emotional functioning (4.4 +/- 1.4 vs. 5.7 +/- 1.0, p < 0.01), symptoms (1.6 +/- 0.8 vs. 5.8 +/- 1.2, p < 0.01), and in the ESS (13.7 +/- 6.5 vs. 3.9 +/- 3.8, p < 0.01). Regarding the patients' symptoms, improvement was noticed for "sleepiness while watching a spectacle" (96%), "reading" (95%), "carrying on a conversation" (95%), "driving" (92.9%), "restless sleep" (87.8%), and "urinating more than once per night" (84.8%). Smaller improvements were observed for the reported "dry mouth-throat upon awakening" (36.1%),"excessive fatigue" (54.5%), and "decreased energy" (55.3%).We conclude that OSAS patients who adhere to nighttime CPAP therapy show significant improvement of their quality of life, daytime sleepiness, and other symptoms after 6 months of treatment with CPAP.