ABC of arterial and venous disease - Vascular complications of diabetes
ABC of arterial and venous disease - Vascular complications of diabetes
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DOI：
10.1136/bmj.320.7241.1062
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发表时间：
2000-04-15
影响因子：
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通讯作者：
Morris, AD
中科院分区：
文献类型：
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作者：
Donnelly, R;Emslie-Smith, AM;Morris, AD
成年糖尿病患者的年死亡率约为5.4%（非糖尿病成年人的两倍），他们的预期寿命平均减少5-10年。虽然死亡率的增加主要是由于心血管疾病，但非心血管原因造成的死亡也在增加。糖尿病的诊断立即增加了发展各种临床并发症的风险，这些并发症在很大程度上是不可逆的，并且是由于微血管或大血管疾病。糖尿病病程是并发症发病的重要因素，但其他危险因素如高血压、吸烟和高胆固醇血症与糖尿病相互作用，影响微血管病变和大血管病变的临床进程。
Adults with diabetes have an annual mortality of about 5.4%(double the rate for non-diabetic adults), and their life expectancy is decreased on average by 5-10 years. Although the increased death rate is mainly due to cardiovascular disease, deaths from non-cardiovascular causes are also increased. A diagnosis of diabetes immediately increases the risk of developing various clinical complications that are largely irreversible and due to microvascular or macrovascular disease. Duration of diabetes is an important factor in the pathogenesis of complications, but other risk factors—for example, hypertension, cigarette smoking, and hypercholesterolaemia—interact with diabetes to affect the clinical course of microangiopathy and macroangiopathy.