Neuroimaging evidence for cortical involvement in the preparation and in the act of swallowing
Neuroimaging evidence for cortical involvement in the preparation and in the act of swallowing
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DOI：
10.1016/s1053-8119(03)00285-4
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发表时间：
2003-09-01
期刊：
影响因子：
5.7
通讯作者：
Pantev, C
中科院分区：
文献类型：
--
作者：
Dziewas, R;Sörös, P;Pantev, C
本研究采用全脑磁成像和合成孔径磁强计研究了自发性和反射性吞咽水的准备和执行以及简单的舌头运动的皮层地形。在运动执行方面，自发性吞咽水时，中外侧初级感觉运动皮层的激活向左强烈偏侧，反身性吞咽水时向左偏侧较弱，而舌头运动时则完全不偏侧。相比之下，在准备自发性吞咽水和舌头运动时，初级感觉运动皮层显示了双侧激活。在反身性吞水之前，没有观察到激活。左侧脑岛和额盖的激活仅在自愿吞咽水的准备和执行过程中观察到。这些新发现表明，人类的吞咽皮层控制是由左半球主导的。(C) 2003 Elsevier Inc.版权所有。
This study employed whole head magnetoencephalography and synthetic aperture magnetometry to investigate the cortical topography of the preparation and the execution of volitional and reflexive water swallowing and of a simple tongue movement. Concerning movement execution, activation of the mid-lateral primary sensorimotor cortex was strongly lateralized to the left during volitional water swallowing, less strongly lateralized to the left during reflexive water swallowing, and not lateralized at all during tongue movement. In contrast, the preparation for both volitional water swallowing and tongue movement showed a bilateral activation of the primary sensorimotor cortex. No activation was seen prior to reflexive water swallowing. Activation of the left insula and frontal operculum was observed only during both the preparation and the execution of volitional water swallowing. These new findings suggest a left hemispheric dominance for the cortical control of swallowing in humans. (C) 2003 Elsevier Inc. All rights reserved.