CONSTITUENTS OF SINDORA SUMATRANA MIQ .1. ISOLATION AND NMR SPECTRAL-ANALYSIS OF SESQUITERPENES FROM THE DRIED PODS
CONSTITUENTS OF SINDORA SUMATRANA MIQ .1. ISOLATION AND NMR SPECTRAL-ANALYSIS OF SESQUITERPENES FROM THE DRIED PODS
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DOI：
10.1248/cpb.42.138
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发表时间：
1994-01-01
影响因子：
1.7
通讯作者：
SUPRIYATNA, S
中科院分区：
文献类型：
--
作者：
HEYMANN, H;TEZUKA, Y;SUPRIYATNA, S
苏门答腊干豆荚中中性组分的研究。结果分离出3个新的倍半萜类化合物（2、6和8）和9个已知的倍半萜类化合物（1、3、4、5、7、9、10、11a和12a），其中3个（7、10和12a）为首次从天然来源中分离得到。另一种化合物，4-豆甾醇-3- 1(13)（连同甾醇混合物；β -谷甾醇，豆甾醇和油菜甾醇）也得到了。所有分离得到的倍半萜类化合物均采用以二维核磁共振技术为主的波谱方法进行了结构鉴定，发现化合物具有石竹烷、葎草烷、丁香烷和环己烷骨架。并对分离得到的倍半萜的核磁共振数据进行了讨论。
Investigation of the neutral fraction of the dried pods of Sindora sumatrana MIQ. has resulted in the isolation of three new sesquiterpenoids (2, 6 and 8) together with nine known ones (1, 3, 4, 5, 7, 9, 10, 11a and 12a), of which three (7, 10 and 12a) are reported for the first time from a natural source. One other compound, 4-stigmasten-3-one (13) (together with a sterol mixture; beta-sitosterol, stigmasterol and campesterol) was also obtained. The structures of all the isolated sesquiterpenes were determined bg means of spectroscopic methods, mainly tao-dimensional NMR techniques, and the compounds were found to have the caryophyllane, humulane, clovane and caryolane skeletons. The NMR data of the isolated sesquiterpenes are also discussed.