Coxsackie B4 infection and islet cell antibodies three years before overt diabetes.
Coxsackie B4 infection and islet cell antibodies three years before overt diabetes.
复制标题
柯萨奇 B4 感染和胰岛细胞抗体三年前出现明显糖尿病。
DOI：
10.1016/s0022-3476(82)80067-x
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发表时间：
1982
期刊：
影响因子：
--
通讯作者：
Palmer,JP
中科院分区：
文献类型：
--
作者：
Asplin,CM;Cooney,MK;Crossley,JR;Dornan,TL;Raghu,P;Palmer,JP
这是一个病例报告，在对250个家庭进行的前瞻性研究过程中发现了一个患有胰岛素依赖型糖尿病的儿童。每隔4个月采集一次血清标本，检测科萨基B3、B4和B5病毒以及胰岛细胞抗体。这个孩子在这些抗体出现3年后出现糖尿病，当时也发现了科萨基B抗体。作者认为这种疾病不太可能是由病毒引起的。阿波斯托洛夫
This is a case report on a child with insulin-dependent diabetes discovered in the course of a prospective study conducted on 250 families. Serum specimens were collected at 4-monthly intervals and assayed for Coxsackie B3, B4and B5viruses and also islet cell antibodies. In this child the diabetes appeared 3 years after the demonstration of these antibodies, when Coxsackie B antibodies were also found. The authors think it unlikely that the illness was caused by the virus.K. Apostolov.