Enantioselective ring opening of meso-epoxides with tetrachlorosilane catalyzed by chiral bipyridine N,N'-dioxide derivatives
Enantioselective ring opening of meso-epoxides with tetrachlorosilane catalyzed by chiral bipyridine N,N'-dioxide derivatives
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DOI：
10.1016/s0040-4039(02)02229-3
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发表时间：
2002-12-02
影响因子：
1.8
通讯作者：
Hashimoto, S
中科院分区：
文献类型：
--
作者：
Nakajima, M;Saito, M;Hashimoto, S
在二异丙基乙胺存在下，利用手性联吡啶 N,N'-二氧化物作为催化剂，内消旋环氧化物与四氯硅烷进行对映选择性开环，得到相应的氯代醇，对映选择性高达 90% ee。 (C) 2002 Elsevier Science Ltd. 保留所有权利。
An enantioselective ring opening of meso-epoxides with tetrachlorosilane in the presence of diisopropylethylamine exploiting chiral bipyridine N,N'-dioxides as catalysts affords the corresponding chlorohydrins in high enantioselectivities of up to 90% ee. (C) 2002 Elsevier Science Ltd. All rights reserved.