Small bowel bacterial overgrowth: a negative factor in gut adaptation in pediatric SBS.
Small bowel bacterial overgrowth: a negative factor in gut adaptation in pediatric SBS.
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DOI：
10.1007/s11894-007-0059-3
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发表时间：
2007-12-01
影响因子：
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通讯作者：
Ziegler, Thomas R
中科院分区：
文献类型：
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作者：
Cole, Conrad R;Ziegler, Thomas R
小肠细菌过度生长（SBBO）在患有短肠综合征（SBS）的婴儿和儿童中很常见。它的发生是由于解剖结构，运动和分泌的改变，这促进了细菌的异常生长。SBBO与重要的临床问题相关，包括长期依赖肠外营养、肝损伤和吸收不良。一个主要的临床挑战是正确诊断细菌过度生长。对这种疾病的管理仍然知之甚少，应该进行充分的评估。本文综述了目前对肠道细菌的认识以及与小儿SBS细菌过度生长相关的问题。
Small bowel bacterial overgrowth (SBBO) is common in infants and children with short bowel syndrome (SBS). Its occurrence is due to alterations in anatomy, motility, and secretion, which promote the abnormal growth of bacteria. SBBO is associated with significant clinical problems, including prolonged dependence on parenteral nutrition, liver injury, and malabsorption. A major clinical challenge is in making the correct diagnosis of bacterial overgrowth. Management of this disorder is still poorly understood and should be evaluated adequately. This review addresses the current understanding of bacteria in the intestines and issues related to bacterial overgrowth in pediatric SBS.