SCOP, structural classification of proteins database: Applications to evaluation of the effectiveness of sequence alignment methods and statistics of protein structural data
SCOP, structural classification of proteins database: Applications to evaluation of the effectiveness of sequence alignment methods and statistics of protein structural data
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DOI：
10.1107/s0907444998009172
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发表时间：
1998-11-01
期刊：
影响因子：
--
通讯作者：
Chothia, C
中科院分区：
文献类型：
--
作者：
Hubbard, TJP;Ailey, B;Chothia, C
蛋白质结构分类 (SCOP) 数据库提供了所有已知蛋白质结构关系的详细而全面的描述。分类是在等级层面上进行的：前两个层面，科和总科，描述近和远的进化关系；第三个，折叠，描述几何关系。迄今为止，进化关系与蛋白质物理和化学关系之间的区别是该数据库独有的特征。该数据库可用作校准序列搜索算法和生成蛋白质结构群体统计数据的数据源。该数据库及其相关文件可从 URL http://scop.mrc-lmb 镜像的许多 WWW 站点免费访问。 cam.ac.uk/scop/。
The Structural Classification of Proteins (SCOP) database provides a detailed and comprehensive description of the relationships of all known protein structures. The classification is on hierarchical levels: the first two levels, family and superfamily, describe near and far evolutionary relationships; the third, fold, describes geometrical relationships. The distinction between evolutionary relationships and those that arise from the physics and chemistry of proteins is a feature that is unique to this database, so far. The database can be used as a source of data to calibrate sequence search algorithms and for the generation of population statistics on protein structures. The database and its associated files are freely accessible from a number of WWW sites mirrored from URL http://scop.mrc-lmb. cam.ac.uk/scop/.